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Hepatocyte growth factor may prevent UV-induced tumor cells. (News Front).

* Hepatocyte growth factor (or scatter factor) may help maintain cell life and skin barrier function without inducing cancer after UV damage, according to Dr. Erwin Tschaler, professor of dermatology at Vienna Medical School and scientific director of Chanel's CE.R.I.E.S. (Epidermal and Sensory Research and investigation Center). Due to signaling pathways (PI-3 kinase and MAP kinase), hepatocyte growth factor signals cells to divide and differentiate into specialized roles, including the preservation of UV-damaged cells.

"As the name scatter factor suggests, this cytokine encourages cells to become more mobile and `scatter,'" said Dr. Tschaler. "It also seems to encourage the invasion of the extracellular matrix by cells. We believe that hepatocyte growth factor helps maintain the skin's barrier function without allowing for UV-damaged cells to develop into tumor cells."
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Publication:Household & Personal Products Industry
Date:Jul 1, 2002
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