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Hepatitis C patients with history of alcoholism can still receive liver transplants, study finds.

Patients infected with hepatitis C (HCV) are potential candidates for liver transplantation, even if they have a history of alcoholism, researchers report in the October issue of Digestive Diseases and Sciences.

Adrian Di Bisceglie, MD, and colleagues at the St. Louis University School of Medicine in Missouri reviewed the records of 107 patients who underwent liver transplantation. Thirty-one had chronic HCV infection alone, 24 had liver disease secondary to the consumption of more than 80 g/day of alcohol for at least 10 years, 11 had both chronic HCV infection and alcoholic liver disease, and 41 received transplants for other reasons. After a mean follow-up period of 29 months, no significant differences among the groups were noted with regard to either patient or graft survival. Overall, 26% of the patients died during follow-up, while another 10% required retransplantation.

"Although alcoholism may accelerate the progression of liver disease in chronic hepatitis C patients, it does not appear to adversely affect the outcome, at least in the short-term, and these patients appear to be good candidates for liver transplantation," the authors concluded.
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Comment:Hepatitis C patients with history of alcoholism can still receive liver transplants, study finds.
Publication:Transplant News
Geographic Code:1USA
Date:Dec 10, 1999
Words:180
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