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Healthy People at Risk With High-Sugar Diet.

A recent study found changes in fat metabolism that are associated with an increased risk of cardiovascular disease in men who consumed a high-sugar diet. *

The study included men with nonalcoholic fatty liver disease (NAFLD) and healthy men with a low amount of liver fat. On a daily basis for 12 weeks, participants were given diets that contained an equal amount of total calories but provided either 650 or 140 of those calories from sugar.

Men with NAFLD who received the high-sugar diet exhibited changes associated with a greater risk of cardiovascular disease. Among men who did not have NAFLD who were given the high sugar diet, liver fat increased and fat metabolism became more like that of individuals with NAFLD.

Editor's Note: "A high intake of sugars produced changes in the lipoprotein metabolism of controls that were characteristic of men with NAFLD," the study authors observe. "These findings indicate that the accumulation of liver fat can influence the plasma lipid and lipoprotein response to dietary sugars, and provide new evidence for a mechanism to explain how sugars may contribute to NAFLD and dyslipidemia (an abnormally high amount of lipids in the blood)."

* Clin Sci (Lond). 2017;131(21):2561-73.

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Title Annotation:In The News
Publication:Life Extension
Article Type:Brief article
Date:May 1, 2018
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