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The Hospital for Sick Children (HSC) has wrangled two prominent scientists into its research institute and away from the Montreal Neurological Institute and McGill University -- the husband and wife team of David Kaplan and Freda Miller.

Kaplan's research focuses on cellular signalling and its role in normal and defective neural function. While a scientist in the U.S., he led the group that identified the Trk/nerve growth factor receptor, which is crucial for the development and survival of many nerve cells. He has also discovered proteins that may be used by Trk to stop the growth of brain tumours, and could lead to new methods of treating this cancer. Currently, Kaplan's research group is investigating the ability of Trk to block the growth of neuroblastoma and medulloblastoma, tumours that commonly arise in children.

In collaboration with Miller's research group, Kaplan is also working on determining how the nervous system develops and regenerates following injury, both of which are important goals for discovering novel treatments for neurological diseases and injuries such as those to the spinal cord.

Freda Miller will build on her stem cell research as a senior scientist in HSC's developmental biology and brain and behaviour research programs. Miller made headlines last year with her discovery that stem cells can be harvested from human adult skin; a possible alternative to the more controversial embryonic stem cells.

"The faculty at the HSC are among the best in the world. As an American, I felt that the quality of research, the willingness of Canadians to work together, and the potential far breakthroughs at HSC and in the Toronto scientific community are as good as the best centres in the U.S. such as Harvard and Stanford," said Kaplan, a senior scientist and the new head of cancer research in the HSC Research Institute. Kaplan and Miller also hold appointments as professors in the department of molecular and medical genetics and the Institute of Medical Science at the University of Toronto.

Michael Hill is new executive director of the Canadian Association of Chemical Distributors (CACD), effective June 12, 2002. Hill arrives at the CACD with more than 30 years' experience in the producer sector of the Canadian chemical industry, and has been an active supporter of CACD, as a supplier partner. CACD is an association of chemical distributors with 47 member companies representing in excess of 3,000 employees in Canada.

Sarah Cooney, a graduate of the University of Toronto with a bachelor's degree in genetics and a master's in botany, has been appointed journals manager for the Society of Chemical Industry (SCI) at its international headquarters. Cooney has worked with Elsevier Science and for Nature Publishing Group. Publications she has worked on include Current Opinion in Chemical Biology, Chemistry & Biology, Cell Press, The Lancet and Nature. Her experience covers editorial production and management roles.
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Title Annotation:Hospital for Sick Children retains David Kaplan, Freda Miller
Comment:Health. (Personals/Personnalites).(Hospital for Sick Children retains David Kaplan, Freda Miller)
Publication:Canadian Chemical News
Article Type:Brief Article
Geographic Code:1CANA
Date:Oct 1, 2002
Words:474
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