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HAUSER RESPONDS TO RECENT TAXOL CONCERNS IMPACTING STOCK PRICE

 HAUSER RESPONDS TO RECENT TAXOL CONCERNS IMPACTING STOCK PRICE
 BOULDER, Colo., June 26 /PRNewswire/ -- In response to recent market concerns resulting from the release of written testimony from Bristol-Myers Squibb Co. (Bristol) (NYSE: BMY) to the Senate Energy and Natural Resources Committee regarding the "Pacific Yew Act," Hauser Chemical Research Inc. (NASDAQ: HAUS) has announced that there is no impact on its relationship with Bristol or the company's activities in producing taxol. The testimony does not represent any change in direction from Bristol's and Hauser's stated objectives in the past.
 Hauser Chemical Research has produced taxol since 1987 and operates the only commercial scale Good Manufacturing Practices (GMP) production facilities for bulk taxol for human use. Production from its facilities should exceed 130 kilograms per year by calendar year end and can be readily expanded to over 230 kilograms per year providing an important competitive advantage in the future. Hauser's long term contract with Bristol provides for minimum revenues of $56 million from taxol production over a three-year period. As announced last spring, Hauser has developed a method for production of taxol from yew needles and twigs from yew plantations, which are planned substitutes for the current source.
 According to Hauser's Chief Executive Officer Dr. Dean P. Stull, "As part of its agreement with the National Cancer Institute, Bristol continues to pursue the development of alternative sources for taxol, including work by both Hauser Chemical Research and others. Bristol is moving rapidly in five or six areas at the same time, while still anticipating the collection of bark from the wild for three to five years for taxol production." According to Dr. Zola Horovitz, vice president business development and planning at Bristol-Myers Squibb, "We also are collaborating with Hauser on a number of projects."
 Hauser is actively involved in several areas including the isolation of taxol and taxol precursors from yew grown in commercial plantations. According to Stull, "Hauser has developed technology for production of several taxol precursors including 10-deacetylbaccatin III, which can be used in the semi-synthesis of taxol. We are preparing for commercial production of these from several yew sources. When taxol's potential is fully realized, we anticipate that production of taxol will rely on a variety of raw materials, with Hauser continuing in its key role."
 Hauser Chemical Research is a chemical processor, specializing in the extraction and purification of high value natural products using its proprietary technologies. Additionally, through Hauser Laboratories, the company provides interdisciplinary laboratory testing services, chemical engineering services and contract research and development. The company is based in Boulder.
 -0- 6/26/92
 /NOTE TO EDITORS: Hauser has recently prepared a report on taxol entitled "Taxol: From Research to Reality" which is available from its Investor Relations Department at 303-443-4662, Ext. 1030.
 /CONTACT: Dean P. Stull or William E. Paukert of Hauser Chemical Research, 303-443-4662/
 (HAUS BMY) CO: Hauser Chemical Research Inc.; Bristol-Myers Squibb Co. ST: Colorado IN: MTC HEA SU:


BB-MC -- DV002 -- 4108 06/26/92 09:30 EDT
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Publication:PR Newswire
Date:Jun 26, 1992
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