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Guiding growth. (Horizons).

Repair of peripheral nerve injuries is limited by the growth of neuromas and fibrous tissue into the anastamosis. This results in incomplete regeneration and thus incomplete return of neurologic function. A bioresorbable product that shields the nerve while allowing regeneration would afford improved outcomes in this difficult situation. Polyganics has recently placed such a product in clinical trials in centers across the world.

The peripheral nerve guide, a transparent synthetic tube, is sutured to both ends of the transected nerve. As the nerve regrows, it is protected in the tube. After regeneration is complete, the tube is gradually resorbed into the body. This represents an important alternative to using grafts from elsewhere in the body or from animal-derived products.

Clinical trials are expected to be closed this year, and FDA approval is expected in 2003. Polyganics has several other products under study for similar uses in other specialties.


(2002). Press Release: Polyganics starts clinical trials with its transparent and bioresorbable peripheral nerve guide. Polyganics. Inc.
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Title Annotation:bioresorbable peripheral nerve guide by Polyganics
Publication:Journal of Neuroscience Nursing
Article Type:Brief Article
Geographic Code:4EUNE
Date:Feb 1, 2003
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