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Grapefruit and Zocor don't mix.

Research published in the medical journal Neurology suggests that eating a grapefruit each morning may have triggered a serious side effect in a 40-year-old woman taking the popular anticholesterol drug Zocor. Study authors note that similar drugs known as statins could also be influenced by grapefruit consumption.

Grapefruit contains a chemical that inactivates a liver enzyme involved in the metabolism of Zocor and other drugs. As a result, regular consumption of the fruit can lead to excessively high blood levels of the drug. Grapefruit and grapefruit juice are also known to interact with Plendil Extended-Release tablets and Procardia (calcium channel blockers), Premarin (a hormone preparation), and Xanax (for anxiety and panic), according to the 2004 Physicians' Desk Reference Companion Guide.
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Title Annotation:Cardiovascular News At A Glance
Publication:Saturday Evening Post
Article Type:Brief Article
Date:Nov 1, 2004
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