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Gluteal implant and lymphoma report.


PATIENTS with textured silicone gluteal implants could be at risk of anaplastic large cell lymphoma, based on a possible case in a patient diagnosed 1 year after implant placement.

The 49-year-old woman was initially diagnosed with anaplastic lymphoma kinase-negative ALCL via a lung mass and pleural fluid before bilateral gluteal ulceration occurred 1 month later, reported Orr Shauly of the University of Southern California in Los Angeles, and his colleagues.

Soft-tissue disease and fluid accumulation around the gluteal implants suggested that the lung mass had metastasized from primary neoplasia in the gluteal region. If ALCL did originate at the site of the gluteal implants, it would represent a first for silicone implant-associated ALCL, which has historically been associated exclusively with breast implants.

'As many as 200 cases of [breast implant-associated ALCL] have been described worldwide, with a majority in the context of cosmetic primary breast augmentation or cancer-related breast reconstruction with the use of a textured implant (57% of all cases)," the investigators wrote in Aesthetic Surgery Journal.

"Recently however, it has been hypothesized that the relationship of ALCL with the placement of textured silicone implants may not [be] limited to the breast due to its multifactorial nature and association with texturization of the implant surface," they added.

The authors reported having no . conflicts of interest and the study dal not receive funding.

SOURCE: Shauly 0 et al. Aesthet Surg J. 2019 Feb 15. doi: 10.1093/asj/sjz044.


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Author:Pass, Will
Publication:Dermatology News
Date:May 1, 2019
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