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Genes (and proteins) in the bank.

Genes (and proteins) in the bank

Improvements are being made in the computer programs used to compare the sequences of the components that make up proteins and DNA, decreasing both the time and computer memory required to search for similarities, reports William R. Pearson of the University of Virginia in Charlottesville. He and his colleagues have devised new methods to compare proteins or genes analyzed by different laboratories and entered into computerized data banks. For example, he says, with an IBM PC microcomputer, DNA sequences totaling 4 million nucleotides can now be searched for a given sequence in less than an hour. And a protein data bank containing 700,000 amino acids can be searched in less than 10 minutes. "Computer analysis of DNA and protein sequences has become increasingly important as our ability to clone and sequence genes has outstripped our ability to identify their functions," he says.
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Title Annotation:computerized data banks in genetic and protein research
Publication:Science News
Date:Apr 5, 1986
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