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Gap junctions in the brain; physiological and pathological roles.

9780124159013

Gap junctions in the brain; physiological and pathological roles.

Ed. by Ekrem Dere.

Academic Press

2013

304 pages

$149.95

Hardcover

QP376

In addition to chemical links across synapses, neurons can also form direct connections via electrical gap junctions. These channels play a key role in brain development and intercellular communication. Dere (pathophysiology of cerebral aging, U. Pierre et Marie Curie, Paris; AP-HP Hopital Charles Foix, Centre de Recherche et Developpement, Ivry-sur-Seine, France) introduces types of gap junctions, their structural aspects, expression patterns of connexins (transmembrane proteins), and gap junction-related diseases due to mutations in connexin genes. International researchers working in this emerging field discuss specific connexin genes and their mechanisms of action and function in the developing neocortx, behavior, and neurological and neuropsychiatric diseases. The text includes color and b&w illustrations including schematic representations and models. Academic Press is an imprint of Elsevier.

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Publication:Reference & Research Book News
Article Type:Book review
Date:Feb 1, 2013
Words:152
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