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Fructose and abdominal pain in children.

Two hundred twenty-two children (aged 2-19 years; mean age, 10.5 years) with chronic abdominal pain underwent a fructose hydrogen breath test, using 1 g of fructose per kg of body weight (maximum, 25 g). Fifty-five percent of the patients had a positive test (an increase of breath hydrogen of more than 20 parts per million above baseline), and were placed on a low-fructose diet. Seventy-seven percent of those patients reported a resolution of symptoms on the low-fructose diet. Of the 101 patients with a negative fructose hydrogen breath test, 54.4% reported a resolution of symptoms without a low-fructose diet.

Comment: Fructose intake has increased substantially during the past 30 years, primarily because of increased consumption of high-fructose corn syrup. The results of the present study suggest that fructose intolerance/ malabsorption is common in children with recurrent abdominal pain, and that a low-fructose diet is an effective treatment for many such children.

Escobar MA Jr et al. Fructose intolerance/malabsorption and recurrent abdominal pain in children. J Pediatr Gastroenterol Nutr. 2014;58:498-501.

by Alan R. Gaby, MD

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Title Annotation:Literature Review & Commentary
Author:Gaby, Alan R.
Publication:Townsend Letter
Article Type:Brief article
Date:Jun 1, 2015
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