Printer Friendly

Feinstein Institute secures USD1.65m to identify and examine vagus nerve's role in sepsis.

M2 EQUITYBITES-August 17, 2018-Feinstein Institute secures USD1.65m to identify and examine vagus nerve's role in sepsis

(C)2018 M2 COMMUNICATIONS http://www.m2.com

Medical research company Feinstein Institute for Medical Research reported on Thursday the receipt of a USD1.65m grant from the National Institutes of Health (NIH) to examine the vagus nerve's role in the inflammation and metabolism associated with sepsis, a body-wide immune system reaction to an infection responsible for deaths.

This five-year, USD1.65m NIH R01 grant was awarded to the institute's medical research professor Valentin A. Pavlov, PhD.

Having a better understanding of the nervous system's signalling during sepsis could lead to the identification of new therapeutic targets within bioelectronic medicine, which combines neuroscience, molecular biology and bioengineering to tap into the nervous system to treat disease and injury without pharmaceuticals.

In conjunction, the previous research conducted by Dr Pavlov and Feinstein Institute president and CEO Dr Kevin J. Tracey, MD, found that the brain and the vagus nerve are involved in controlling immune responses and inflammation - this discovery has been called the inflammatory reflex.

Dr Pavlov's team plans to map the neural signals coming from the brainstem through the vagus nerve to the body's organs during sepsis. In this new study, he will examine the role of the vagus nerve originating in the brainstem in the regulation of immune responses and metabolism during sepsis.

Through combined work, Feinstein's researchers have identified a protocol, which includes early administration of fluids and antibiotics, to implement across Northwell Health's 23 hospitals. As a result, sepsis-related mortalities at those facilities have been reduced by almost 70%.

((Comments on this story may be sent to info@m2.com))

COPYRIGHT 2018 Normans Media Ltd.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2018 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Publication:M2 EquityBites (EQB)
Date:Aug 17, 2018
Words:280
Previous Article:Medical Properties Trust's board approves USD0.25 per share dividend.
Next Article:Nordic Waterproofing Holding posts increased EPS in Q2 2018.
Topics:

Terms of use | Privacy policy | Copyright © 2021 Farlex, Inc. | Feedback | For webmasters |