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FNUSA - ICRC device for capturing nanoparticles and their handling.

Contract award: FNUSA - ICRC device for capturing nanoparticles and their handling.

Technology instruments for particle capture and manipulation method uses MST (micro-scale thermophoresis), which can be traced nano-molecules and change their mobility. They are thus measured changes in mobility of molecules in a microscopic temperature gradients. The technology is extremely sensitive because it detects changes in size, charge and hydration envelope molecules. The technology aims to determine which inhibitors studied proteins is also appropriate to further test and optimize their structure. This method will monitor the interaction of the inhibitor to the protein in the cell extracts. Comparing with the terms of monitoring the interaction of purified proteins can assume, whether the inhibitor of non-specific uptake by other proteins, metabolism or other process reduces the amount of the inhibitor bound to the target protein or enzyme. MST technology will give us the opportunity to accelerate the process of finding a suitable candidate, the method is time-consuming, Optimizable, provides a measurement of dissociation constants of bonds, stoichiometry and binding energy and allows to detect protein aggregation, which could adversely affect the relevance of the received parameters. Results can be monitored in real-time measurement is automated.

Date of contract award decision: 16.3.2015

Total final value of contract(s)Value: 2 892 500 CZK Excluding VAT

Contractor name : BIOTECH A.S.,

Contractor address : Ul. TymiEinovEi 619/14,

101 00 Praha,

Financier : European Union (EU)

Implementing agency : FakultnE[degrees] nemocnice u sv. Anny v Brne


PekarskEi 664/53

Contact point(s): Odbor prEivnE[degrees]ch vecE[degrees]

For the attention of: Mgr. Matej BE[bar]ril

656 91 Brno


Telephone: +420 543183283


Fax: +420 543183285

Internet address(es):

General address of the contracting authority:

Address of the buyer profile:

Electronic access to information:

Country :Czech Republic

Email :

Url :

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Publication:Mena Report
Date:Mar 23, 2015
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