FDG-PET in mantle cell lymphoma involving skin / Deri tutulumlu mantle hucreli lenfomada FDG-PET.
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MCL commonly involves extranodal sites. Skin involvement occurs in only 2%-6% of all cases of MCL but is seen in 17% of stage IV patients. The blastoid types MCL are more aggressive than MCL and associated with a worse clinical outcome. Only a few cases with blastoid variant MCL and skin involvement have been described in English literature. In MCL, FDG-PET detects more disease sites, nodal as well as extranodal, than conventional imaging methods, resulting in a higher sensitivity (1-3).
Written informed consent was obtained from the patient.
Conflict of Interest
No author of this paper has a conflict of interest, including specific financial interests, relationships, and/or affiliations relevant to the subject matter or materials included in this manuscript.
Address for Correspondence: M.D. Mehmet Sonmez, Department of Hematology, School of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey Phone: +90 462 377 58 48 E-mail: mesonmezqtyahoo.com
(1.) Hutchings M, Specht L. PET/CT in the management of haematological malignancies. Eur J Haematol. 2008;80:369-80.
(2.) Estrozi B, Sanches JA Jr, Varela PC, Bacchi CE. Primary cutaneous blastoid mantle cell lymphoma-case report. Am J Dermatopathol. 2009;31:398-400.
(3.) Motegi S, Okada E, Nagai Y, Tamura A, Ishikawa 0. Skin manifestation of mantle cell lymphoma. Eur J Dermatol. 2006;16:435-8.
Mehmet Sonmez (1), Umit Cobanoglu (2), Savas Karyagar (3), Bircan Sonmez (4)
(1) Department of Hematology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey
(2) Department of Pathology, School of Medicine, Karadeniz Technical University, Trabzon, Turkey
(3) Department of Nuclear Medicine, Trabzon Numune Training and Research Hospital, Trabzon, Turkey
(4) Department of Nuclear Medicine, School of Medicine, Karadeniz Technical University, Trabzon, Turkey
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|Title Annotation:||Images in Hematology|
|Author:||Sonmez, Mehmet; Cobanoglu, Umit; Karyagar, Savas; Sonmez, Bircan|
|Publication:||Turkish Journal of Hematology|
|Date:||Dec 1, 2010|
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