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Explaining Revascularization Risks in Heart Patients with Cancer.

Angioplasty and stenting (percutaneous coronary intervention, or PCI) is generally a safe revascularization procedure. But patients who have, or have had, cancer are at increased risk for complications. An article published ahead of print on Nov. 30, 2018, in the European Heart Journal spells out these complications and their associated cancers. The authors used data from the Nationwide Inpatient Sample to examine the association between four forms of cancer--lung, breast, colon and prostate--and in-hospital mortality and complications in more than 6.5 million PCI procedures performed in the U.S. from 2004 to 2014. They found that patients with active lung cancer had the poorest outcomes from PCI and the highest risk of in-hospital complications and mortality. Current colon cancer patients had an increased risk of complications in general and bleeding in particular. Patients with active prostate cancer were also at increased risk of bleeding. Metastatic cancer increased these risks four- or fivefold. At the other end of the spectrum, patients with active breast cancer had no increased risk over patients who did not have cancer, perhaps because they tended to be younger and healthier overall. These findings will help physicians ensure that cancer patients needing revascularization are appropriately treated, carefully watched for complications and not denied PCI inappropriately.

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Title Annotation:HEART BEAT
Publication:Heart Advisor
Date:Feb 22, 2019
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