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Estrovera relieves hot flashes and other menopausal symptoms.

Metagenics, San Clemente, CA, has introduced Estrovera--an all-natural dietary supplement formulated to address the needs of menopausal women--to the North American market. The key active ingredient in Estrovera is ERr 731, a phytoestrogen extract of Siberian rhubarb root.

In a randomized, double-blind, placebo-controlled study of 112 perimenopausal women with menopausal symptoms, subjects who took 4 mg of ERr 731 (equivalent to one Estrovera tablet) daily for 12 weeks experienced a statistically significant reduction in hot flashes per day (12 at baseline and 2 at study end) vs. placebo (12 at baseline and 13 at study end). The product also demonstrated a statistically significant improvement vs. placebo in all 11 menopausal symptoms in the Menopause Rating Scale (MRS).

ERr 731 was first introduced in 1993 in Germany, where it continues to be widely recommended by healthcare providers. It is one of the most thoroughly researched natural compounds for managing menopausal symptoms, according to Metagenics.
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Title Annotation:Research Highlights
Publication:Nutraceuticals World
Article Type:Clinical report
Date:Jun 1, 2010
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