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Endothelin in renal physiology and disease.


Endothelin in renal physiology and disease.

Ed. by Matthias Barton and Donald E. Kohan.

S. Karger, AG


266 pages



Contributions to nephrology; v.172


For nephrologists, internists and other healthcare professionals, renal physiologists, molecular biologists, researchers, students, and scientists in drug research and development, Barton (molecular internal medicine, U. of Zurich, Switzerland) and Kohan (nephrology, U. of Utah Health Sciences Center) compile 21 articles reviewing experimental concepts, preclinical studies, and clinical data on the association between endothelin and kidney disease. Specialists in pharmacology, molecular biology, physiology, cardiovascular medicine, and nephrology in Europe, the US, and Asia cover the pharmacology, molecular biology, and physiology of endothelin in the kidney; the role of endothelin and endothelin receptor antagonists (ERAs) in renal disease, including renal inflammation and hypertension, sickle cell disease, and polycystic kidney disease; and the current state of clinical development of ERA therapy in renal medicine, such as for those with resistant hypertension and hypertension nephropathy, diabetic nephropathy, and nondiabetic chronic kidney disease.

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Publication:Reference & Research Book News
Article Type:Brief article
Date:Dec 1, 2011
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