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Endocrine disruptor concerns.

The 22 endocrine-disrupting substances ChemSec added to the SIN list are: 3-benzylidene camphor, 4-meth-ylbenzylidene camphor, 4-nitrophenol, p-nitrophenol, benzophenone-l, benzophenone-2, benzophenone-3, butyl-paraben, dicyclohexyl phthalate, diethyl phthalate, dihexyl phthalate, ethylhexyl methoxycinnamate, metam natrium, methyl tertiary butyl ether (MTBE), pentachlorophenol, perchloroethylene, propylparaben, quadrosilan, resorcinol, tert-butylhydroxyanisole (BHA), thiram, and zineb.

ChemSec said it added the 22 substances to the list because they are "as worrisome as other SVHCs," persist in the environment, have complex effects especially when present in combination, and are "increasingly linked to a range of health problems."

John Peterson Myers, a co-author of the 1996 book on endocrine disruptors, Our Stolen Future, said the current regulatory approach based on setting safe levels for exposure to chemicals was not suitable for endocrine disruptors because their effect on human genes was unpredictable, in some cases posing a greater hazard at lower exposure than at higher exposure.

Regulating endocrine disruptors on a case-by-case basis may also be inadequate, Myers said, citing the recent ban in the European Union on the use of bisphenol A (BPA) in infant feeding bottles. In some cases, Myers said, the EU ban has resulted in BPA being replaced with a similar substance, bisphenol S.

ChemSec said the REACH law tended to prioritize controls on carcinogenic, mutagenic, and reprotoxic substances (CMRs) along with persistent, bioaccumulative, and toxic substances (PBTs) over endocrine disruptors.

However, REACH requires the European Commission by mid-2013 to review the conditions under which endocrine disrupting substances listed as SVHCs can be granted au-thorizations for further use, and this could be an opportunity to more tightly control the substances, ChemSec said.
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Title Annotation:Regulatory and Legislative News
Publication:JCT CoatingsTech
Date:Jun 1, 2011
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