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Emerging medications can help stabilize plaque for secondary prevention.

While prospectively detecting and treating vulnerable plaque remains a challenge, some medications, current and emerging, can help stabilize plaque for secondary prevention, according to a European Society of Cardiology (ESC) position paper" by the ESC Working Group of Atherosclerosis and Vascular Biology published online in Thrombosis and Haemostasis. The researchers noted in the paper that "strong clinical evidence has shown the ability of statins to stabilize plaque, along with positive results for aspirin and other antiplatelet agents, beta-blockers, and renin-angiotensin-aldosterone system inhibitors" and the presence of "some evidence showing plaque stabilization abilities for peroxisome proliferator activated receptor (PPAR) agonists, niacin, omega-3 fatty acids, and some HDL-raising therapies.

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Publication:Pulse International
Article Type:Report
Date:Aug 14, 2011
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