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Embryonic stem cells created with human cloning technology.

WASHINGTON, May 15 Kyodo

A team of scientists based in the United States has succeeded for the first time in creating cloned human embryonic stem cells that can develop into different types of specialized cells, according to an article posted online Wednesday.

The article in U.S. journal Cell said the team used a technique known as somatic cell nuclear transfer, involving the replacement of nuclei in human ova with nuclei from donor skin cells, "generating embryos that are almost an identical genetic match to the donor individual."

A South Korean scientist in 2004 announced the creation of cloned ES cells using human ova, but the claim later proved to be fake.

Research on cloned ES cells became less active following the generation of induced pluripotent stem cells, or iPS cells, around 2006.

Masahito Tachibana, a researcher at Oregon Health & Science University who is part of the team, said, "It is possible that such ES cells could have fewer genetic defects than iPS cells."

According to the article, the team used 126 ova donated by nine women aged between 23 and 31 in the United States in a project authorized by a college ethics committee.

ES cells were successfully produced from six of the 126 ova, with four of the six ova provided by one woman, it said.

The university also succeeded in creating cloned ES cells using monkey ova in 2007.
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Publication:Japan Science Scan
Date:May 20, 2013
Words:232
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