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Effects of orofacial myofunctional therapy on the symptoms and physiological parameters of sleep breathing disorders in adults: a systematic review.


Orofacial myofunctional therapy (OMT) is a set of techniques and procedures intended to change orofacial muscular and functional patterns using isotonic and isometric exercises for orofacial and oropharyngeal muscles targeting the functions of breathing, mastication, swallowing and speech (1).

For the past 10 years, Speech, Language and Hearing Sciences intervention using OMT have been presented in this field as one of the possible treatments for snoring and obstructive sleep apnea (OSA), with evidence found specially in studies on Sleep Breathing DIsorders in adults (1-4).

Every new field of study with its specific techniques needs researches that provide evidence of the benefits of each therapy. The first publications on OMT for obstructive sleep apnea date from 1999 (5), but the first randomized clinical trial (RCT) to use the therapy as alternative treatment for patients with moderate OSA was published in 20091. The study reported a decrease of approximately 40% in the Apnea and hypopnea index (AHI), a reduction in cervical circumference, reduction in snoring intensity and frequency, reduction of daytime sleepiness and better sleep quality after the OMT program. Right after this first international publication, the same journal published an editorial questioning the benefits and objectives of OMT procedures for improving OSA (6).

Physiologically, the pharynx is a highly collapsible area in the entirety of its extension. The activity of dilating pharynx muscles, especially the genioglossus and tensor palatini muscles oppose to the tendency of the pharynx to collapse as a protective mechanism. Changes in such mechanism are associated with the syndrome of obstructive sleep apnea disorder (7). In that sense, OMT applied to OSA has the objective of strengthening the nasopharynx and oropharynx musculature contributing to reduce collapse of the airway during sleep (1-4). However, the exact mechanisms by which OMT helps with Sleep Breathing Disorders are still not clear to this day.

Contemporary studies show OMT efficient results in improving the quality of life (2), in the reduction of intensity and frequency of snoring (3) and in the better adherence of CPAP (Continuous Positive Airway Pressure) (4). Such studies endorse the Speech, Language Therapist interest in this field and validate the presence of that professional in the interdisciplinary realm of Sleep Breathing Disorders, especially in Brazil with the existence of a specific certification for Speech, Language and Hearing Sciences in the field of sleep disorders (8)

At the present stage, systematic reviews are necessary to attest the level of scientific evidence of OMT effects in OSA and in snoring, as well as to set methodological parameters for the decision-making in therapy matters. However, such parameters are not always clear or coincident, making difficult a consistent verification of OMT effects for individuals with Sleep Breathing Disorders.

The objective of this study is to systematically analyze the scientific literature available on OMT programs for adults with Sleep Breathing Disorders, their effects on symptoms and physiological parameters, trying to argue for the relevance of the practice-based evidence (PBE).


Research strategies

The fundamental questions that guide this literature review are:

"What are the methodological parameters in orofacial myofunctional therapy programs for Sleep Breathing Disorders?"

"What are the effects of the isolated orofacial myofunctional therapy in adults considering symptoms and physiological parameters of Sleep Breathing Disorders?".

Our search was performed in the following online databases: "Literatura Latino-Americana e do Caribe em Ciencias da Saude" (Lilacs); "Medical Literature Analysis and Retrieval System Online" (MEDLINE), "US National Library of Medicine National Institutes Health" (Pubmed), "Cochrane Library" (Cochrane) and "Scientific Electronic Library" (Scielo) and we have selected the studies published between the year 2000 and April 2017.

The descriptors in Health Sciences (DeCs) used for retrieving the articles, language limiters considered for Portuguese and English languages, were: apneia obstrutiva do sono (obstructive sleep apnea) [All fields]; terapia miofuncional (myofunctional therapy) [All fields]; exercicios (exercises) [All fields]; exercicios orofaringeos (oropharyngeal exercises) [All fields]; exercicios respiratorios/ /exercicios da via aerea (breathing exercises / upper airway exercises [All fields]; Fonoaudiologia (Speech, Language and Hearing Sciences / speech therapy) [All fields]. The search was performed with associated descriptors (e/and).

Selection criteria

The selection of studies published followed the steps described below:

The search for materials according to the associate descriptors and that had been published between the year 2000 to 2017 (April) in the referred databases with full version available online; the selection of studies whose titles and abstracts were related to the proposed subject; observation of inclusion and exclusion criteria; reading and analysis of the full text articles.

The considered articles should published in Portuguese or English and approach the methodological parameters for the OMT programs related to Sleep Breathing Disorders or present studies describing the procedures and effects of isolated OMT in adults considering the symptoms and physiological parameters of Sleep Breathing Disorders (snoring and/or OSA) necessarily reporting polysomnographic data (pre and post therapy), at least for the Apnea and Hypopnea Index (AHI).

Repeated articles recovered from different databases were not considered. An initial selection was made after reading of titles and abstracts and exclusion of those that did not match the criteria. The full text articles were downloaded and the studies were read and analyzed in their entirety. The references were evaluated, the studies were identified and listed.

Data analysis

The following topics were tabulated for the articles' analysis: name of authors, year of publication, information on the type of study, study risk of bias (considering selection, performance, detection, friction and publishing biases), number of subjects, demographic characteristics (gender, age), type of Sleep Breathing Disorder, level of OSA severity, methodological parameters with respect to therapeutic procedures and description of results post OMT.

A specific protocol was developed for the present research based on the selected articles and trying to answer the question on the methodological parameters that guide OMT proposals for Sleep Breathing Disorders.

The specific research protocol based on methodological parameters included:

Therapeutic parameters: procedures, frequency and period of therapy, therapy follow up;

Parameters for evaluation and reevaluation:

Physiologic parameters: anthropometric measurements such as body mass index (BMI) and cervical circumference (cc) pre and post OMT, polysomnographic data such as Apnea and Hypopnea Index (AHI) for each hour of sleep and minimum blood oxygen saturation (SpO2) and period with SpO2 under 90% pre and post OTM;

Symptomatology: data on daytime sleepiness (Epworth Sleepiness Scale) (9) and snoring reported by complaint or part of Berlin questionnaire (referring to intensity and frequency) (10).


One hundred and twenty four articles were screened considering the methodology for this literature review, initially excluding the studies that did not involve snoring and/or OSA (N=28) and that did not provide some form of therapy (N=67). 29 potentially relevant studies were set apart and their references checked for other studies not present in our initial search. 10 more studies were included. After verifying the total of 39 articles, 31 of them were eliminated and 8 articles were kept for detailed analysis.

The fluxogram (Figure 1) illustrates the trajectory of the present study. It is interesting to point out that 4 studies involve specifically the applicability and results of OMT for children (11-14), two case-control reports (13, 14) and two retrospective studies (11, 12).

Considering the focus of the present systematic literature review on the effects of isolated OMT for adults with OSA, 8 studies were considered, two of them with systematic literature review (15, 16), three RCT (1-4), one clinical study (17) and two case reports (18, 19). A description of the studies can be found in Tables 1 and 2.

The two systematic literature reviews listed in our search differ in relation to the objectives and criteria of analysis (Table 1). Data from the literature review (16) performed through meta-analysis attest for the positive effects of OMT in adults based in parameters from polysomnography, indicating approximately 50% decrease in AIH, improvement in minimum blood oxygen saturation and snoring. However, the systematic literature review previously published (15), with focus in the increase of muscle tonus with exercises did not present favorable effects for AIH reduction under five (15). We should reinforce that given the criteria of the described literature review potential results above this level were not considered as they would be later (16), understanding that the AIH criteria under five events per hour indicates remission of the disorder.

Considering two of the RCTs (2, 4), they originally correspond to the same study and although they bring additional information, the data are from the same subjects and so were counted only once in our systematic literature review.

The three RCT were analyzed reported on Table 2 observing, when possible, the possibility of bias according to the Cochrane Collaboration criteria for the development of systematic reviews of interventions (20). Little information on this item could be recovered in the complete version of the published articles or even in the respective thesis, which were secondarily checked. To give an example, only one of the studies (3) mentions the intention of treating, which is recommended in the cases of dropout or loss of subjects in the RCT and this being a better model for this type of study. The RCT also presented performance bias in the blinding of the professionals performing the clinical evaluations pre and post OMT. That is something important to be taken into account in future studies.

The last three studies: the clinical study (17) and the case reports (18, 19) do not provide data related to possible biases. For the present literature review all types of studies were analyzed despite possible biases.

Data related to the establishment the studies' sample, type of Sleep Breathing Disorder, level of severity of the OSA and therapeutic parameters can be found in Table 3.

The three RCT (1-4) counted on a control group as intended for this type of study. The subjects did not undergo OMT, only receiving orientations and/ or nasal wash as placebo effect in order to minimize performance bias. Trying to analyze the effects of OMT associated to other forms of therapy, other studies (2, 4) have considered four groups, one control group (N=24), one OMT group (N=27), CPAP (N=27) and a mixed group (CPAP e OTM) (N=22). This literature review considered only the results referring to OMT alone, following the methodological criteria.

The analysis section of the studies (1-4, 17) did not include sample calculation, which we consider to be a relevant matter. The challenge of gathering a relevant number of participants in the groups, especially for this kind of studies is a known fact, mainly in the search for homogeneity in the sample. However, observing the number of subjects in the clinical studies' OMT group, we notice a gradual increase in that aspect through the years, which we consider to be a positive factor.

The Sleep Breathing Disorders and their level of severity have also changed through the years. Starting with clinical case reports of severe OSA (19, 20), going to RCT with moderate OSA1, to mild or moderate OSA (3, 17) to RCT (2, 4) with all three levels of OSA severity. We were able to notice that the search for data on OMT effects has grown for all levels of OSA.

Regarding the methodological therapeutic parameters applied to each of the studies (1-4, 17, 19), the approach and procedures in OMT were the same considering the period of therapy, being prescribed 12 sessions, one time per week. They differ nevertheless in the selection of exercises, number of repetitions, frequency and period of daily practice and also in the type of functional approach. The specificities of the practices were not properly justified regarding the choices made in each of the studies.

The analysis section of the case reports are clearly more specific and direct considering the case matter. On those studies, the selected exercises are not described, nor is the amount of exercises. On the RCTs those descriptions are found. On one of the case reports (17) the amount of exercises changes along three stages of practice: 13 exercises for the two first stages and seven for the third one. The other three RCTs (1-4) seem to suggest the following up of exercises and functional practice progress without considering stages. Two of the studies indicate programs with a higher amount of exercises (1, 2, 4) and another (3) shows a great reduction of such number, maybe trying to facilitate the technique for the patient or because of the main focus of the study, which was primary snoring.

It is important to indicate that mostly because of the type of study, techniques were previously defined and equally applied for the entire study group in each of researches regardless of the myofunctional changes that each of the participants could present. For RCT studies that is a required procedure in order to observe the effects of a certain technique. However, studies with consistent justification for the exercise selection and its functional approach seem to be necessary to better fund the therapeutic practice targeted to those cases.

The description of therapeutic parameters only similar among the studies is probably due to the variety of aspects and matters that involve a orofacial myofunctional therapeutic approach, besides the recent presence of such therapy in the field of sleep disorders.

Other relevant data refer to the follow up of the studies in relation to the effects obtained with OMT. Only one of the studies in the present systematic review brought this important concern (2, 4), revealing a downsize of the results previously obtained. Considering that the follow up was only after a few weeks, it was possible to attest the necessity of maintaining the therapy program to solidify the results previously obtained. New studies, with medium and long term follow ups seem to be necessary.

The data regarding the methodological parameters for evaluation and reevaluation post OMT are found in Tables 4 and 5. Considering this aspect, the randomized trials follow similar parameters for evaluation and reevaluation and they are based on symptomatology data, specific anthropometric data and polysomnographic data.

Table 4 shows the data of the results obtained with OMT based in physiologic parameters and they show significant differences in relation to anthropometric measurements considering the reduction in cervical circumference without BMI reduction in three clinical studies (1, 3, 17). The authors indicate that the improvement in oropharynx musculature may have determined such reduction since the subjects did not lose weight and their BMI was not altered.

Considering physiologic data obtained with polysomnography, all three RCT (1-4) revealed significant differences in OMT showing decrease in AIH. It is worth to point out that in one of the studies (3), which also considered subjects with primary snoring and mild OSA, the relevant statistic difference was only for the subjects with moderate OSA. The author justifies that the AIH for mild OSA is already close to the minimum limit and thus not provide significant reduction.

The two articles with case reports (18, 19) are the ones presenting a better improvement in the level of apnea with great differences in AIH, maybe because they had an individual focus. Those studies also present improvement in the minimum SpO2, as well as in one of the ECR1 and the clinical essay (17), indicating one other relevant beneficial effect of OMT.

In order to analyze the effects of OMT on snoring in an instrumental way, a RCT (3) measured snoring recording it with a microphone and then presented a total snoring index considering sound intensity divided by the total period of sleep. The analysis of such data pre and post OMT, comparing the results in both groups (therapy and control) showed significant reduction of snoring considering the snoring index and also considering the total snoring index in the OMT group (3).

The results in the studies referring to the symptomatology pre and post OMT are found in table 5, which brings the data in quality of life, quality of sleep, excessive daytime sleepiness, intensity and frequency of snoring, reported and analyzed with specific questionnaires.

Only one of the RCT2 brought data on quality of life using three different questionnaires (FOSQ21, WHOQoL-Bref (22) and SF-36 (23)). Comparing the results of the group pre and post OMT. Significant differences were found in: physical domain of the instrument WHOQoL-Bref and functional quality of the SF-36, revealing the effects of OMT in those aspects.

The observation of the quality of sleep was reported in two studies (1, 3) using the Pittsburgh (24) questionnaire. The data show improvement with significant differences post OMT, although not indicating in which components specifically.

The data on the symptom of daytime sleepiness were based on the Epworth Sleepiness Scale (ESS) (9) in four of the clinical essays (1-4, 17) and in one of the case reports19. Excluding the results in one of the RCT (3), the studies indicate a significant reduction of the symptom after a OMT program.

Considering the data related to snoring, the clinical studies analyzed the intensity and frequency of the snoring according to the Berlin questionnaire (1, 3, 17) or the analogic subjective visual scale (4). They indicate a reduction in intensity (1, 3, 4, 17) and frequency of snoring (1, 3, 4). One of the RCT (3) separates the Berlin questionnaire answers when applied to the subject himself or his roommate, showing significant improvement in the answers of the roommate when comparing pre and post data for the OMT and the control group. In general terms, the report on snoring by the patient himself is uncommon and when it happens is due to information previously given by the roommate. He is the one that listens to the subject snoring and is able to report on changes and is thus the most relevant information for that variable.

In relation to the case reports, one of them (19) analyzed excessive daytime sleepiness and snoring data in two cases. The data followed the Epworth Sleepiness Scale (ESS) and show a relief of the symptom. The data on snoring, on its turn, followed a scale of 0 to 4 (0 = absence of snoring, 1= resonate; 2 = light snore, 3 = snoring disturbing partner, 4 = snoring disturbing family). In both cases there was a reduction in the symptom post OMT. The other case report (18) only brings information on high intensity snoring and the report of sleepiness previous to OMT, going to moderate snoring after OMT with evidence on polysomnographic data. The lack of data uniformity does not allow us to infer how those characteristics related to the effects of OMT in the study.

Considering the data in general, it is worth noticing that the clinical study (17) and one of the RCTs (3, 4), statistical analysis were presented in terms of mean and standard deviation. However, two of the RCTs (1, 3, 4) included median, minimum and maximum, probably because of the number of subjects in the sample. Methodological differences were also identified between the RCTs (1-4) and the clinical study (17). The RCTs compared changes pre and post OMT between the study and control groups after the indicated period and the results were statistically analyzed. The clinical study brought statistical analysis considering the changes in study group post OMT compared with data from previous evaluation. Regardless of those methodological differences, which can difficult the comparison of results, the studies confirm the positive effects of OMT for patients with OSA.

Systematic literature reviews are a growing tendency in the field of health sciences as to gather evidence on the practice of a certain line of action, trying to base changes in the works of prevention, diagnosis, treatment and rehabilitation. The privilege of a systematic literature review is the possibility of a detailed approach focused on answering precise questions. In the field of Speech, Language and Hearing Sciences, that is already a challenge, given the variety of the aspects involved in each of the fields of competence (25, 26). However, sleep studies in that context are a recent and interdisciplinary field of work and the search for literature reviews that recover the effects of therapies is necessary to guide upcoming studies as well as the clinical practice.

The present systematic literature review found that there are few controlled randomized trials with adults and they are necessary to provide scientific evidence to guide the eligibility criteria for undergoing OMT and also determine the applicable therapy procedures.


The present systematic literature review shows that the methodological parameters guiding orofacial myofunctional therapy programs for Sleep Breathing Disorders mostly compare data pre and post therapy based on the analysis of: symptomatology related to quality of life, quality of sleep, daytime sleepiness, intensity and frequency of snoring; anthropometric data related to body mass index and cervical circumference; physiological parameters measured with polysomnography related to Apnea and Hypopnea Index and blood minimum saturation.

The parameters for therapy are related to the practice of exercises for the orofacial and oropharynx musculature daily, reinforced by functional practice for the period of 3 months, with individual therapy one time per week.

The most relevant effects of the isolated orofacial myofunctional therapy in adults include: reduction of daytime sleepiness and snoring, better quality of sleep, partial decrease in the Apnea and Hypopnea Index and partial increase in the blood minimum saturation.

There have been few controlled randomized blind trials and they are important to attest the effects of the technique based on evidences and guiding the therapeutic decisions considering evaluation and diagnosis and the phenotype of the patient for an accurate prognosis.


Coordination for the Improvement of Higher Education Personnel (CAPES) National postdoctoral program in the Program of Graduate Studies in Speech Language Pathology and Audiology (PEPG/PUC-SP) at the Pontificate Catholic University of Sao Paulo.


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(2.) Diaferia G, Badke L, Santos-Silva R, Bommarito S, Tufik S, Bittencourt L. Effect of speech therapy as adjunct treatment to continuous positive airway pressure on the quality of life of patients with obstructive sleep apnea. Sleep Med. 2013;14(7):628-35.

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Fabiane Kayamori [1]

Esther Mandelbaum Goncalves Bianchini [1]

[1] Pontificia Universidade Catolica de Sao Paulo (PEPG-PUCSP), Sao Paulo, SP Brazil.

Research support source: National Postdoctoral Program/ Coordination for the Improvement of Higher Education Personnel (PNPD/CAPES).

Conflict of interest: Nonexistent

Received on: August 29, 2017

Accepted on: October 17, 2017

Mailing address:

Fabiane Kayamori

Alameda Jau, 1767, conjunto 51,

Cerqueira Cesar

CEP: 01420-002 - Sao Paulo,

Sao Paulo, Brasil

Caption: Figure 1. Systematic literature review information fluxogram: studies selection stage
Table 1. Eligible literature review articles description

                                                      Number of
Author, year        Objective         Meta-analysis    listed

Camacho et      Systematic                 Yes             9
al, 2015 (16)   literature review
                considering OMT
                for the treatment
                of OSA in children
                and adults
                meta-analysis of
                of polysomnography,
                snoring and

Valbuza et      Literature review           No              3
al, 2010 (15)   on methods of
                treatment for
                OSA improving
                musculature tonus
                as revealed in
                the AHI.

Author, year        Objective

Camacho et      Systematic               Data on the
al, 2015 (16)   literature review        adults:
                considering OMT          myofunctional
                for the treatment        therapy reduces
                of OSA in children       AHI in
                and adults               approximately
                performing               50%, improves
                meta-analysis of         Sp[O.sub.2] and
                of polysomnography,      snoring.
                snoring and

Valbuza et      Literature review        No accepted
al, 2010 (15)   on methods of            scientific evidence
                treatment for            that the methods
                OSA improving            are effective for
                musculature tonus        AHI decrease
                as revealed in           under 5.
                the AHI.

Table 2. Eligible clinical studies description considering type of
study and biases

                          Selection   Selection     Performance
                            bias        bias           bias

Author, year    Type of
                study      Random                   Participants and
                          sequence     Omitted        professional
                          generator   allocation       blinding

Diaferia G       RCT      unknown      unknown      yes (participants)
et al,                                              no (professional
2013 (12)                                           speech therapist)
and 2016 (14)

Verma et al,     CR         NR           NR               NR
2016 (17)

Ieto et al,      RCT      unknown      unknown      yes (participants)
2015 (3)                                            no (professional
                                                    speech therapist)
                                                    yes (participants)

Guimaraes et     RCT      unknown      unknown      no (professional
al, 2009 (1)                                        speech therapist)

Silva et al,     CR         NR           NR                NR
2007 (18)

Pitta et al,    CR2         NR           NR                 NR
2007 (19)       cases

                  Detection          Attrite      Report
                    bias              bias         bias

Author, year                                     Selective
                Final reviewers    Incomplete     results
                  blinding          results       report

Diaferia G           yes            unknown       unknown
et al,          (polysomnography)
2013 (12)
and 2016 (14)

Verma et al,        NR                NR             NR
2016 (17)

Ieto et al,          yes            unknown       Treatment
2015 (3)        (polysomnography)                recommendation,
                                                 low risk of bias

Guimaraes et         yes            unknown         unknown
al, 2009 (1)    (polysomnography)

Silva et al,         NR                NR              NR
2007 (18)

Pitta et al,         NR                NR              NR
2007 (19)

Subtitles: CR=case report; CE=clinical study; RCT=randomized clinical
trial; NR=no record

Table 3. Description of data from the studies considering
subjects characterization, type of disorder and level
of OSA severity and therapeutic parameters

Author, year        Subjects characterization
                    in the studies                      Type and
                                                       severity of
                     N    Gender             Age         the OSA

Diaferia et         27     male            45.2         mild,
al, 2013(2)                               [+ or -]     moderate
and 2016(4)                                13.0        and severe

Verma et al,        20     male (75%)       41.1         mild and
2016(17)                   female (25%)   [+ or -]      moderate
                                            10.6          OSA

Ieto et al,         19     male (57.9%)      48         snoring,
2015(3)                    female (42.1%)  [+ or -]     mild and
                                             14         moderate

Guimaraes et        16     male              63         Moderate
al, 2009 (1)                                              OSA

Silva et al,        1      female            60         Severe OSA

Pitta et al,        1      male              37         Severe OSA
                    1     female             55         Severe OSA

Author, year                                                Follow up
                 Therapeutic              Frequency/
                 procedures               Period of OMT

Diaferia et      Exercise program:        12 sessions     After 3
al, 2013 (2)     Tongue, soft palate,     3 daily         weeks wash
and 2016(4)      pharynx musculature,     practices, 20   out: decrease
                 facial musculature.      minutes each      in AHI
                 Functional: breathing,
                 swallowing and

Verma et al,     3 stages exercise        12 sessions           NR
2016(17)         program:Tongue, soft     10 repetitions
                 palate, facial           5 series per
                 musculature and          day
                 mandible musculature.

Ieto et al,      Nasal washShort          12 sessions           NR
2015(3)          exercise program         Daily practice
                 Tongue, soft             3 times a day,
                 palate, facial           8 minutes each

Guimaraes et     Nasal washExercise       12 sessions           NR
al, 2009(1)      program:Tongue, soft     Daily practice
                 palate, facial           30 minutes each
                 musculature and
                 mandible musculature.
                 Functional: speech,
                 breathing, swallowing
                 and mastication

Silva et al,     Nasal washExercises      12 sessions           NR
2007(18)         forTongue, soft          Note.:1st PSG
                 palate, facial           10 months
                 musculature.             previous to
                 Functional: Breathing    therapy)
                 and mastication

Pitta et al,     Exercises for Tongue,    16 sessions           NR
2007(19)         soft palate, pharynx
                 musculature, facial      16 sessions           NR
                 musculature and
                 mandible musculature.

Subtitles: N = number of subjects; OSA = obstructive sleep apnea;
OMT = orofacial myofunctional therapy; AHI = Apnea and hypopnea
Index per hour of sleep; NR = no record; PSG = Polysomnography

Table 4. Description of data considering the results with
orofacial myofunctional therapy (OMYT) based on physiological

                         Anthropometric measurements

Author, year          BMI (kg/[m.sup.2])

                      pre                      post

Diaferia G            25.0[+ or -]7.4          26.7[+ or -]2.9
et al, 2013 (2)
and 2016 (4)

Verma et al,          25.6[+ or -]3.1          25.4[+ or -]3.2
2016 (17)

Ieto et al,           28.1[+ or -]2.7          28.2[+ or -]2.8
2015 (3)

Guimaraes et          29.6[+ or -]3.8          29.5[+ or -]4.3
al, 2009 (1)

Silva et al.             23.3                     NC
2007 (18)

Pitta et al.             26.3                     27.7
2007 (19)                22.2                     22.2

                         Anthropometric measurements

Author, year          CC (cm)

                      pre                  post

Diaferia G            41.6[+ or -]3.7      41.5[+ or -]2.3
et al, 2013 (2)
and 2016 (4)

Verma et al,          38.4[+ or -]1.3      37.8[+ or -]1.6 *
2016 (17)

Ieto et al,           37.9[+ or -]2.5      37.5[+ or -]2.4 **
2015 (3)

Guimaraes et          39.6[+ or -]3.6      38.5[+ or -]4.0 *
al, 2009 (1)

Silva et al.             NC                       NC
2007 (18)

Pitta et al.             NC                       NC
2007 (19)                NC                       NC


Author, year          AHI (events/hour)

                      pre                  post

Diaferia G            28[+ or -]22.7       13.9[+ or -]18.5*
et al, 2013 (2)
and 2016 (4)

Verma et al,          20.1[+ or -]9.1      19.7[+ or -]9.4
2016 (17)

Ieto et al,           25.4 (22.1-          18.1 (15.4-
2015 (3)                 28.7) #              24.1) # ***

Guimaraes et          22.4[+ or -]4.8      13.7[+ or -]8.5 *
al, 2009 (1)

Silva et al.             44                       3
2007 (18)

Pitta et al.             48.5                     8.6
2007 (19)                40.4                     3.3


Author, year          Minimum Sp[O.sub.2] (%)

                      Pre                  post

Diaferia G            83.7 [+ or -]7.7     84.9[+ or -]8.8
et al, 2013 (2)
and 2016 (4)

Verma et al,          87.6 [+ or -]1.1     88.5 [+ or -]1.6 *
2016 (17)

Ieto et al,
2015 (3)              85.5[+ or -]7.5      83.8[+ or -]8.9

Guimaraes et            83[+ or -]6          85[+ or -]7 *
al, 2009 (1)

Silva et al.             83                       92
2007 (18)

Pitta et al.             79                       87
2007 (19)                77                       83

Subtitles: Data presenting mean and standard deviation. except for #.
which presents the results in median. minimum and maximum; BMI=body
mass index; CC=cervical circumference; AHI= Apnea and Hypopnea
Index per hour of sleep; Sp[O.sub.2] = blood minimum saturation;
* P significant (<0.05) test T; ** P significant considering test
with variation according to period and group; *** P relevant
only for the group with moderate OSA; NR=no record.

Table 5. Description of data considering the results with
orofacial myofunctional therapy (OMT) based on
symptomatological parameters


Author. Year            Life quality
                        Sleep quality

                        pre                      post

Diaferia G et           FOSQ WHOQoL-             FOSQ WHOQoL-
al. 2013 (2)            Bref SF-36 (2)           Bref *
and 2016 (4)                                     SF-36 *

Verma et al.            NC                       NC
2016 (17)

Ieto et al.             Pittsburgh               Pittsburgh
2015 (3)                6[+ or -]3.2             4[+ or -]2.6 *

Guimaraes               Pittsburgh               Pittsburgh
et al. 2009 (1)         10.2[+ or -]3.7          6.9[+ or -] 2.5 *

Silva et al.            NR                       NR
2007 (18)

Pitta et al.            NR                       NR

2007 (19)               NR                       NR


Author. Year            ESS

                        pre                      post

Diaferia G et           13.7[+ or -]3.2 (2)      7.5[+ or -]3.7 *
al. 2013 (2)
and 2016 (4)

Verma et al.            15.4[+ or -]2.3          13.6[+ or -]3.1 *
2016 (17)

Ieto et al.             7 (3-11) #               7 (4-10) #
2015 (3)

Guimaraes               14[+ or -]5              8[+ or -]6 *
et al. 2009 (1)

Silva et al.            NR                       NR
2007 (18)

Pitta et al.            12                       10

2007 (19)               13                       7


Author. Year            Intensity of snoring

                        pre                      post

Diaferia G et           8.5[+ or -]2.3 (4)       4.9[+ or -]3.2 *
al. 2013 (2)
and 2016 (4)

Verma et al.            2.8[+ or -]0.5           1.7[+ or -]0.6 *
2016 (17)

Ieto et al.             2(2-3) S                 2(1-2) S
2015 (3)                4(2.5-4) C #             1(1-2)C * #

Guimaraes               3(3-4)                   1(1-2)*
et al. 2009 (1)         #                        #

Silva et al.            NR                       NR
2007 (18)

Pitta et al.            Disturbs the             mild
2007 (19)               Disturbs the             mild


Author. Year            Frequency of snoring

                        pre                      post

Diaferia G et           7.7[+ or -]2.3 (4)       4.3[+ or -]2.8 *
al. 2013 (2)
and 2016 (4)

Verma et al.            NC                       NC
2016 (17)

Ieto et al.             3(2-4) S                 2(1-4) S
2015 (3)                4(3-4) C #               2(1.5-3)C * #

Guimaraes               4(4-4)                   3(1.5-3.5) *
et al. 2009 (1)         #                        #

Silva et al.            NR                       NR
2007 (18)

Pitta et al.            NR                       NR

2007 (19)               NR                       NR

Subtitles: Data presenting mean and standard deviation.
except for #. which presents the results in median.
minimum and maximum; ESS=Epworth Sleepiness Scale;
* P significant (<0.05) test T; S=information given by
the subject of the research; C=information provided by
the roommate; NR=no record.
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Title Annotation:texto en ingles
Author:Kayamori, Fabiane; Bianchini, Esther Mandelbaum Goncalves
Publication:Revista CEFAC: Atualizacao Cientifica em Fonoaudiologia e Educacao
Date:Nov 1, 2017
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