Printer Friendly

Ear cells from Japanese bull produces clones after prolonged freezing.

Ear cells from a prize Japanese bull that were frozen and cultured in a lab over several months have successfully produced clones, challenging the notion that cells become too stale to duplicate.

Cells used in cloning generally are either fresh or have had fewer that 10 "passages," or periods in a culture medium. But in the current study, ear cells from 17-year-old bull Kamitakafuku went through up to 15 passages over 3 months before they were used to create calves, according to a report in the January issue of the Proceedings of the National Academy of Sciences. The experiments, performed at the University of Connecticut in Storrs and the Kogashima Prefectural Cattle Breeding Development Institute in Tokyo, Japan, suggest that a library of cells could eventually be used to create clones at any time, even long after the original animals are dead. It also means clones could be produced from cells kept in the laboratory long enough to complete the slow and meticulous process of gene manipulation.

"This is very powerful stuff," said Thomas Wagner, MD, head of cancer research at Clemson University in South Carolina.

The researchers collected Kamitakafuku's ear cells and cultured them for 2 to 3 months. The cells' genetic material then was placed in cow embryos and implanted in surrogate mothers. Four calves were born from cells cultured for 2 months, 2 of which later died--one at birth, the other from a viral infection. Two more clones were born from cells cultured for 3 months.
COPYRIGHT 2000 Transplant Communications, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2000 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:International Pages
Comment:Ear cells from Japanese bull produces clones after prolonged freezing.(International Pages)
Publication:Transplant News
Article Type:Brief Article
Geographic Code:9JAPA
Date:Apr 10, 2000
Previous Article:Neural stem cells showing promise as treatment for aggressive form of brain cancer, scientists find.
Next Article:Courts in US, UK rule in favor of SangStat over Novartis in separate cases involving SangCya.

Related Articles
Japanese clone 8 genetically identical calves from cell of single adult cow.
Japanese scientists report successfully cloning calf from cell of a cloned bull.
Bresagen creates Australia's first cloned pig and files patent application.
After careful preparation, biotech company starts boundary-stretching series of human cloning experiments.
Texas A&M's menagerie of cloned animals could answer many questions.
Cloned fetal cow cells create kidney-like organ that works when transplanted.
In Historic Speech, President Bush Urges Senate to Ban Human Embryo Cloning, But Democratic Leader Says No.
Bull clone puzzles Brazil scientists anticipating a cow.
US scientists create cloned kidney-like cells that survive in cattle.

Terms of use | Privacy policy | Copyright © 2021 Farlex, Inc. | Feedback | For webmasters |