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Drugs that brake the brain.

Drugs that brake the brain

Many mood-altering drugs cause a slowdown of brain metabolism that may play an important role in promoting further drug consumption, according to a report in the January ARCHIVES OF GENERAL PSYCHIATRY.

Edythe D. London of the National Institute on Drug Abuse in Baltimore and her co-workers studied 12 men who reported a history of using two or more illicit drugs. Each received an injection of morphine or saline solution along with radioactively labeled glucose. Positron emission tomography (PET) scans revealed that morphine injections reduced overall glucose utilization in the brain by 10 percent.

In studies by others, PET scans have revealed similar reductions in brain metabolism after people took amphetamines, barbiturates, cocaine or antianxiety drugs. Lowered brain metabolism may be a physiological mechanism that somehow helps to reinforce the continued use of many mood-altering drugs, the researchers conclude.
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Title Annotation:effect of mood-altering drugs
Publication:Science News
Date:Feb 3, 1990
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