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Drug design of zinc-enzyme inhibitors; functional, structural, and disease applications.


Drug design of zinc-enzyme inhibitors; functional, structural, and disease applications.

Ed. by Claudiu T. Supuran and Jean-Yves Winum.

John Wiley & Sons


1022 pages



Wiley series in drug discovery and development


Specialists in drug design and discovery of zinc metalloprotein inhibitors report on research findings that have emerged over the past few years at a level accessible to academic or industrial researchers and to graduate students. They cover carbonic anhydrase inhibitors and activators, matrix metalloproteinase inhibitors, bacterial zinc protease inhibitors, and other enzymes containing zinc. Among specific topics are anti-glaucoma carbonic anhydrase inhibitors as opthalmologic drugs, crystallographic studies of carbonic anydrases from fungal pathogens for structure-assisted drug development, sulfonylated matrix metalloproteinase inhibitors, Clostridium histolyticum collagenase inhibitors in the drug design, angiotensin converting enzyme inhibitors, and inhibitors of histidinol dehydrogenases as antibacterial agents.

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Title Annotation:Wiley series in drug discovery and development
Publication:SciTech Book News
Article Type:Book review
Date:Jun 1, 2010
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