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Depression rates different among dementia subtypes.

PHILADELPHIA -- Rates of depression vary by dementia subtype, Dr. Annette L. Fitzpatrick said in a poster presentation at the Ninth International Conference on Alzheimer's Disease and Related Disorders.

The prevalence of depression among individuals with Alzheimer's disease (AD) has been estimated at about 30%-50% in clinical settings, and somewhat lower in longitudinal studies, she said at the conference, presented by the Alzheimer's Association

In the Cache County Study on Memory in Aging, for example, about 20% of AD patients had suffered with depression in the past month (Am. J. Psychiatry 157[5]:708-14, 2000). The 1-month prevalence in the Cardiovascular Health Study was estimated at 32% (JAMA 288[12]:1475-83, 2002). Less is known about the prevalence of depression in other types of dementia, said Dr. Fitzpatrick of the University of Washington, Seattle.

Data were collected from 32 Alzheimer's disease centers established by the National Institute on Aging in 1984 with the goal of increasing clinical and laboratory research on AD and related dementias. In 1999, a National Alzheimer's Coordinating Center was established to pool the data from all the Alzheimer's disease centers, which now include more than 70,000 patients.

Between 2002 and 2003, the question "Did the subject have depression at the most recent clinical evaluation?" was answered for 12,876 patients aged 55 years and older. The mean age of the group was 76.9 years, 61% were female, and 81% were white. The answer was yes for 14%.

The prevalence of dementia varied widely by subtype of dementia: 11% for probable AD (National Institute of Neurological Disorders and Stroke criteria), 11% for frontal lobe dementia, 19% for vascular dementia, 22% for other AD, 23% for Parkinson's disease dementia, and 35% for progressive supranuclear palsy.
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Title Annotation:Geriatric Psychiatry
Author:Tucker, Miriam E.
Publication:Clinical Psychiatry News
Article Type:Brief Article
Geographic Code:1USA
Date:Oct 1, 2004
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