De Villiers ruled out; RUGBY UNION.
The centre will be sidelined for approximately eight weeks because of a knee injury.
De Villiers underwent checks in Cape Town on Sunday, when the extent of the problem was confirmed.
"Losing our captain is a massive setback," Springboks coach Heyneke Meyer said "Jean has been superb as our leader on and off the field, and he was in excellent form as well. We will certainly miss him next month.
"His injury is the latest in a string of setbacks we've experienced, and with Jaque Fourie also ruled out, it means we will play with a new captain and a new midfield combination next month.
"Luckily we have good depth in the squad at centre, but replacing your captain is always difficult.
"We have a number of good leaders in the squad, but I don't want to rush a decision on the captaincy as we still have to finalise the squad for June."