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DSM comments on EFSA review of vitamin E.

The European Food Safety Authority (EFSA) has concluded that the current Recommended Daily Amount (RDA) of vitamin E should be replaced by a newly defined Adequate Intake (AI). Ingredient supplier DSM responded by highlighting the most recent scientific studies not broadly recognized yet, as well as emphasizing that more research into the micronutrient is needed to precisely define the vitamin E requirement in humans. In particular, this includes the role of vitamin E in protecting polyunsaturated fatty acids (PUFAs) from being oxidized in cell membranes and the beneficial effect of adequate blood levels of vitamin E on cardiovascular health. The new research suggests that individual requirements vary in view of the critical interactions between vitamin E and PUFAs and differ for specific groups, such as pregnant and lactating women, as well as being dependent on factors such as age.

"Whilst we appreciate the work carried out by the EFSA panel in reviewing the Dietary Reference Values (DRV) for vitamin E, it is important to consider all scientific evidence when defining the value. This should include recent research that had been accepted by other well recognized agencies, such as the Institute of Medicine in the U.S. and the D-A-CH report for Germany, Austria and Switzerland," explained Prof. Manfred Eggersdorfer, senior vice president, nutrition science & advocacy at DSM and professor for healthy aging at the University of Groningen, The Netherlands.

"Achieving an optimal status of vitamin E is associated with a number of positive health benefits. Outcomes from the main epidemiological studies show a risk reduction of 24% for cardiovascular events, when comparing high versus low vitamin E concentrations. These results suggest a beneficial effect of vitamin E at a plasma concentration of 30 [micro]mol/L. An increase of the intake recommendation would secure that the general population can reach this status."

The recommended daily intake of vitamin E varies according to the age, gender and criteria applied in individual countries. In the European Union, adult recommendations previously ranged from 4 to 25 mg a-tocopherol equivalents (a-TE)/day for men and from 3 to 12 mg a-TE/day for women. The German-speaking countries (D-A-CH, 2013) have only recently set the recommendation at 12-15 mg alpha-TE/ day for men and 11-12 mg alpha-TE/day for women according to age. As part of its written response to the EFSA panel, DSM highlighted results from a number of observational, prospective studies which suggest that a serum tocopherol concentration of 30 [micro]mol/L and above has beneficial effects on human health in the field of cardiovascular disease and some cancers.

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Title Annotation:Industry News
Publication:Nutraceuticals World
Date:Sep 1, 2015
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