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Cornell study on anesthesia.

Manuel Martin-Flores, MV,, ACVAA, of the Cornell University College of Veterinary Medicine will present preliminary results of his research on safer anesthesia for cats at the annual meeting of the American College of Veterinary Anesthesia and Analgesia in September. Dr. Martin-Flores is one of only 220 anesthesiologists board-certified worldwide by the college.

He has been evaluating antidotes to dexmedetomidine, a drug commonly used as a sedative and painkiller for cats undergoing surgery. "A frequent side effect of dexmedetomidine is bradycardia--slowing of the heart rate--which can be substantial and dangerous during general anesthesia," Dr. Martin-Flores says.

Atipamezole and a drug called MK-467 can be used to reverse those effects. "Veterinarians might attempt to accelerate the heart rate by administering small doses of either antidote," Dr. Martin-Flores says. "Our experience, however, suggests that treatment with atipamezole might be inefficient for increasing the heart rate and that it may also result in considerable arterial hypotension (low blood pressure)."

He found the same result with MK-467. "This means that treatment with these antidotes during general anesthesia might in fact be detrimental and can worsen hemodynamic (blood flow) function in cats," Dr. Martin-Flores says. He hopes the findings will help guide the use of anesthesia in cats and it will become increasingly safer.

His research on MK-467 is ongoing.

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Title Annotation:SHORT TAKES
Publication:Cat Watch
Date:Aug 1, 2016
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