Printer Friendly

Copper 'linked to Alzheimer's'.

COPPER could be a major environmental culprit in the progression of Alzheimer's disease, research published yesterday suggests.

Scientists found strong evidence that copper helps to promote the changes in the brain underlying Alzheimer's.

But they say there is little that can be done about it because copper is so abundant in the diet and also vital to health.

The metal, found in food and drinking water, plays important roles in nerve function, bone growth, the formation of connective tissue, and hormone secretion.

Researchers in the US conducted a series of experiments on mice given trace amounts of copper in their drinking water. In human terms the doses were equivalent to the amount of copper people consume in a normal diet. The study showed that copper accumulating in the brain disrupted the natural removal of toxic amyloid beta protein, which is strongly implicated in Alzheimer's. Copper also directly stimulated neurons that increased the production of amyloid beta, and caused the proteins to clog together in lumps that could not be cleared. Mice with Alzheimer's disease had "leaky" brains that allowed the metal to enter them more freely.

The findings, reported in the journal Proceedings of the National Academy of Sciences, suggested a "one-two punch" both creating more amyloid beta and stopping its removal.
COPYRIGHT 2013 MGN Ltd.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2013 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:Sport
Publication:Western Mail (Cardiff, Wales)
Date:Aug 20, 2013
Words:212
Previous Article:Study reveals rugby players too can get 'punch-drunk' EXPERTS FIND ON-FIELD HEAD INJURIES' LINK WITH DEMENTIA.
Next Article:Militants 'execute' 25 Egyptian police in Sinai.
Topics:

Terms of use | Privacy policy | Copyright © 2019 Farlex, Inc. | Feedback | For webmasters