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ConvergeAnt: An Integrative Approach to Understanding Convergent Evolution in Ant-eating Mammals.

Total cost: EUR 1 880 570

EU contribution: EUR 1 880 570

Topic(s):ERC-CoG-2015 - ERC Consolidator Grant

Objective: Despite its widespread occurrence across the tree of life, many questions still remain unanswered concerning the fascinating phenomenon of convergent evolution. Ant-eating mammals constitute a textbook example of morphological convergence with at least five independent origins in placentals (armadillos, anteaters, aardvarks, pangolins, and aardwolves). The large extent of convergent morphological evolution, the importance of molecular convergence, and the role of the host microbiome in diet adaptation are currently gaining acceptance. However, large-scale comparative studies combining morphology, host genomics, and metagenomics of the associated microbiome are still lacking. In the ConvergeAnt project, we propose taking advantage of the unique set of convergently evolved characters associated with the ant-eating diet to investigate the molecular mechanisms underlying phenotypical adaptation. By using state-of-the art phenotyping methods based on X-ray micro-computed tomography and Illumina sequencing technologies we will combine morphometric, genomic, and metagenomic approaches to evaluate the extent of convergent evolution in the skull of myrmecophagous placentals, in their genomes, and in their associated oral and gut microbiomes. With this ambitious research proposal, we aim at providing answers to longstanding but fundamental evolutionary questions pertaining to the mechanisms of convergent evolution. The ConvergeAnt project will be the first of its kind to apply such an integrative approach to investigate the complex interplay between the mammalian genome and its associated microbiome in a classical case of adaptive convergence driven by a highly specialized diet.

Host Institution

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

France

EU contribution: EUR 1 880 570

Project completion date : 2021-08-31 12:00:00

Major organization : CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

Address : Rue Michel Ange 3

75794 Paris

Country :France

Url : http://www.cnrs.fr/

Financier : EUROPEAN UNION (EU),

Financier address : European Union (EU)

Rue de la Loi 200/Wetstraat 200,

B-1049 Bruxelles/Brussels,

Belgium

Tel: 32-2-2999696, 2993085

Fax: 32-2-2961749

Url: ec.europa.eu/

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Publication:Mena Report
Date:Aug 12, 2016
Words:333
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