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Contract Awarded to Conduct a Prospective Study to Develop a Salivary Biomarker panel that would validate for Stomach Cancer Detection.

Contract Awarded to Conduct a Prospective Study to Develop a Salivary Biomarker panel that would validate for Stomach Cancer Detection

Contract Value: $5 Mn

Contract Completion: Five-Years

The grant was awarded for a five-year project led by Dr. David Wong, associate dean of research and professor of oral biology, and oral biology and medicine at the school. Wong and his team will conduct a prospective study to develop a salivary biomarker panel that would validate for stomach cancer detection. They hope to capture extracellular ribonucleic acid (exRNA), RNA secreted into spaces outside a cell, secreted by stomach cancer cells in saliva samples to confirm whether a patient is at risk of developing this type of cancer.

With this new method, the researchers hope that such risk evaluations could be performed at the dentist%s office in the future.

Wong first discovered salivary exRNA molecules in 2004 and demonstrated their translational utility for detecting oral cancer. Since then, his team has developed salivary biomarkers for a number of oral and systemic diseases, including salivary gland tumors and SjE[micro]gren%s syndrome.

Contractor name : THE UNIVERSITY OF CALIFORNIA, LOS ANGELES SCHOOL OF DENTISTRY

Contractor address : UCLA School of Dentistry,

10833 Le Conte Avenue,

CHS - Box 951668,

Los Angeles,

CA 90095-1668

URL: http://dentistry.ucla.edu

Agency : OWNER:

National Institutes of Health

9000 Rockville Pike

Bethesda,

Maryland 20892

TEL: 301-496-4000,

Email: NIHinfo@od.nih.gov

URL: www.nih.gov

country :United States

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Publication:Mena Report
Article Type:Clinical report
Date:Sep 14, 2013
Words:253
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