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Comparisons of family environment between homeless and non-homeless individuals with schizophrenia in Xiangtan, Hunan.

1. Introduction

Homelessness among individuals with schizophrenia in China is much less common than in high-income countries but it is, nevertheless, is an increasingly important problem in the country, partly due to increased mobility of the population (so family members are dispersed) and partly due to the one-child per family policy (so there are fewer relatives available to care for a mentally ill family member). The limited number of studies about this issue in mainland China focus on the socio-demographic characteristics and physical health of the homeless mentally ill and on their difficulties in obtaining necessary psychiatric treatment. [1] To the best of our knowledge, there has been no research about the original family environment of homeless individuals with schizophrenia in China, a factor that potentially contributes to their homelessness. Noxious family environments and schizophrenic symptoms can exacerbate each other leading to the ejection or departure of the ill individual; in the absence of other family members who can care for the individual or government-supported half-way houses, the ill individual then becomes homeless and, thus, is less likely to receive appropriate treatment. [2] Research about the characteristics of the original families of individuals with mental disorders who become homeless is needed to help characterize high-risk families who should become the focus of preventive interventions aimed at reducing homelessness among patients with serious mental illnesses.

In this study we define homelessness as a period of 7 days or greater in which a person with a confirmed diagnosis of schizophrenia has no place to stay, no source of income, and no social or family support. The study compares the sociodemographic and family characteristics of individuals with schizophrenia who did and did not meet this definition of homelessness. 2

2. Methods

2.1 Subjects

The recruitment of participants for this study is shown in the flowchart in Figure 1. All participants were from the Fifth Ren Min Hospital of Xiangtan, the hospital that is the designated center for the treatment of homeless mentally ill in Xiangtan City, a municipality in Hunan Province with a population of 2.8 million, 72% of whom are rural residents. Between April 2011 and April 2014, a sample of 2439 consecutively admitted homeless inpatients and a convenience sample of 2033 non-homeless inpatients with a diagnosis of schizophrenia were screened for enrollment in the study. Among the homeless individuals, 212 (8.7%) refused to participate, 182 (7.5%) were excluded, and 189 (7.7%) had incomplete data, leaving 1856 (76.1%) who completed the study questionnaire. In the non-homeless group, 198 (9.7%) refused, 84 (4.1%) were excluded, and 23 (1.1%) had incomplete data, leaving 1728 (85.0%) who completed the study questionnaire.

All participants met the following inclusion criteria: a) met the diagnostic criteria for schizophrenia according to the Chinese Classification of Mental Disorders (CCMD-3); [3] b) 18 to 60 years of age; c) had a score of 35 or lower on the Brief Psychiatric Rating Scale (BPRS) [4] (indicating that they were clinically remitted) at the time of the assessment; d) were able to take care of themselves at the time of assessment; e) could comprehend and complete the study questionnaire; and f) signed the informed consent form for the study. Based on their medical records, participants who had organic brain disease, severe physical illness, psychoactive substance dependence, mental retardation, mood disorders, or personality disorders were excluded. 'Homeless' was defined as living on the streets, public places, cars, deserted buildings, and so forth, for at least 7 days prior to the index admission. [4] All homeless participants were brought to the hospital by the police; the police were usually notified about the individuals by local community members and unable to rapidly locate the individual's family, so they transported them to the hospital. The non-homeless group consisted of inpatients with schizophrenia who were not homeless at the time of admission.

2.2 Assessment instrument

The Family Environment Scale (FES) was developed by Moss and colleagues in 1981. FES has been used widely in Western countries to assess the change in family environment before and after family interventions. This study used the third version of the Chinese version of the scale (FES-CV) [5] which had good reliability across patient ratings and family-member ratings when assessing family environment, and had good internal consistency and validity. There are 90 true or false questions in FES-CV, divided into ten 9-item subscales that assess different aspects of the family environment.

The internal consistency (Cronbach's [alpha]) of the ten FES-CV subscales was as follows: cohesion 0.75, expressiveness 0.42, conflict 0.67, independence 0.24, achievement orientation 0.55, intellectual-cultural orientation 0.64, active-recreational orientation 0.57, moral-religious emphasis 0.33, organization 0.63, and control 0.53. The definition of each subscale is as follows. Cohesion: the degree of commitment, help and support the family members provide for each other. Expressiveness: how much family members are encouraged to openly express their emotions. Conflict: the extent to which family members openly express anger and disagreements. Independence: the amount of self-esteem, confidence, and autonomy that family members have. Achievement orientation: the degree to which common activities (for example, going to school or working) are considered measures of achievement and the degree of focus on competition-oriented activities. Intellectual-cultural orientation: the level of interest of family members in political, societal, intellectual, and cultural activities. Active-recreational orientation: the degree of family members' participation in social and recreational activities. Moral-religious emphasis: the emphasis on ethics, religion, and value. Organization: the extent to which family activities and responsibilities are organized and structured. Control: the importance of following family rules and procedures to arrange family life.

The items all have dichotomous responses so the range in subscale scores is 0 to 9, with higher scores indicating a greater tendency to have the trait considered by the subscale. [6]

2.3 Assessment procedure

The FES-CV is a self-report scale that takes less than 30 minutes to complete. This was administered an average of 50 days after the index admission (while the patients were still inpatients). Before the administration of the instrument, trained psychiatrists provided participants with standardized instructions about how to complete the scale. For about 100 illiterate participants in each group, trained psychiatrists read the FES-CV and completed the scale based on respondents' answers. On the same day that the patient completed the FESCV, a trained clinician administered the Brief Psychiatric Rating Scale (BPRS).

2.4 Statistical analysis

All data analyses were conducted using SPSS 17.0. FES-CV subscale scores were continuous measures that approximated normal distributions, so the mean scores of the two groups (i.e., homeless and non-homeless patients) were compared using t-tests. Categorical variables were compared using chi-squared tests.

In order to explore variables that were independently associated with homelessness, two unconditional multivariate logistic regression models were performed. The first model used a backward stepwise procedure to identify socio-demographic variables independently associated with homelessness. The nine socio-demographic variables considered included age, gender (male v. female), occupation (stable job, temporary job, and unemployed), residence (urban vs. rural residence), place of origin (Xiangtan vs. other), marital status (unmarried, married, and divorced or widowed), level of educational (high school or above, middle school, and primary school or below), ethnicity (Han versus other), and severity of psychotic symptoms at the time of the assessment of family functioning (as assessed by the total BPRS score). The second logistic regression entered all 10 subscale scores of the FES-CV after forcing all significant variables from the first model into the expanded model; the goal was to determine which family environment variables were associated with homelessness after adjusting for socio-demographic variables. In the second analysis two variables (residence and place of origin) had to be dropped from the model due to collinearity. The statistical significance level was set at p < 0.05 (two-sided).

3. Results

3.1 Comparison of demographic variables and FES-CV subscale scores

The basic characteristics of participants are shown in Table 1. The gender distribution was similar in both groups and the severity of psychiatric symptoms at the time of the FES-CV evaluation was similar between the two groups, but all the other characteristics were significantly different between the groups. Compared to the non-homeless group, those in the homeless group were older and they were more likely to be rural residents, from outside of Xiangtan, to have a lower level of education, and to be married. The proportion of individuals who had temporary jobs was higher in the homeless group, but the proportion of unemployed individuals was higher in the non-homeless group.

As shown in Table 2, with the exception of the expressiveness subscale, all of the FES-CV subscale scores differed significantly between the two groups. Compared to respondents in the non-homeless group, those in the homeless group reported that their original families had greater achievement orientation, intellectual-cultural orientation, organization, and control; they also reported that their original families had lower levels of cohesion, conflict, independence, active-recreational orientation, and moral-religious emphasis.

3.2 Logistic regression of demographic and family environment risk factors for homelessness in patients with schizophrenia

To identify variables independently associated with homelessness, the aforementioned demographic variables were entered into a logistic regression model, the results of which are shown in Table 3. Eight of the nine variables considered (in Table 1) were significant in the multivariate model. Among this sample of 3574 inpatients with schizophrenia, being homeless at the time of admission was associated with older age, female gender, more severe psychiatric symptoms (at the time of assessing family functioning), rural residence, low educational achievement, residence outside of Xiangtan, being marriage or divorced, and working on a temporary job. There were three differences between the univariate and multivariate results: gender (being female) and severity of psychiatric symptoms became significantly related to homelessness after adjustment for other demographic variables while ethnicity was no longer associated with homelessness after adjustment for the other variables.

The key question for this paper is the extent to which prior family environmental factors are associated with homelessness after controlling for the demographic differences between homeless and non-homeless individuals with schizophrenia. To assess this, the results of all ten FES-CV subscale were entered into a logistic regression model after adjusting for six of the eight socio-demographic variables that were significantly associated with homelessness (shown above). Two variables, urban versus rural residence and living outside of Xiangtan, could not be entered as covariates in the model because of collinearity. As shown in Table 4, with the exception of the conflict and expressiveness subscales, after adjustment of socio-demographic factors all of the other 8 subscale scores were significantly associated with homelessness. Specifically, homelessness was associated with greater organization, intellectual-cultural orientation, achievement orientation, and control; homelessness was also associated with lower levels of independence, cohesion, active-recreational orientation, and moral-religious emphasis. After adjustment the conflict subscale score was no longer significantly associated with homelessness, but the results for all the other subscales were similar to those seen in the univariate analysis (Table 2).

4. Discussion

4.1 Main findings

This study identified a large sample of homeless individuals with schizophrenia and compared them to a sample of individuals with schizophrenia who were not homeless. There were substantial differences in the socio-economic characteristics of homeless and non-homeless patients and in the functioning of their original families--as reported by the patients after their acute psychotic symptoms had resolved.

Homelessness was equally common in men and women but after adjusting for other demographic variables women with schizophrenia were at greater risk of homelessness than men. As expected, homelessness was more common in individuals from rural communities (where social support services are limited), among those who wander away from their communities (i.e., those not from Xiangtan municipality), and among those with limited education (who are less able to mobilize social supports). Homelessness was also associated with greater age; its unclear why this is the case, but it may be that older patients have 'burned their bridges' with relatives and, thus, end up on the streets. Those who had never married (and, thus, were probably still living with parents) were less likely to be homeless while those who were currently married were more likely to be homeless. Finally, patients who reported having temporary employment (i.e., those with no stable income) were more likely to be homeless, while those who reported being unemployed were less likely to be homeless; this may be because formally unemployed individuals (typically only urban residents) may have access to social welfare benefits not available to those in temporary jobs.

Our study found that even after controlling for these socio-demographic variables, family environment--as assessed by the patients themselves using the FES-CV after their acute symptoms resolved--is significantly associated with homelessness among patients with schizophrenia. This finding is consistent with a substantial body of research which has found that family environment, particularly the cohesion and organization of the family, [7] is associated with the onset and course of serious mental illness. Some patients with schizophrenia grow up in noxious family environments which contribute to the emergence and development of their illness. [8,9] Harsh physical and verbal punishment from family members have been associated with the severity of symptoms in individuals with schizophrenia. [10] Addressing these family problems using comprehensive bio-psycho-social interventions can reduce the severity of patients' symptoms, help the patient maintain a stable mood, and prevent relapse. [11,12]

One of the 10 subscales assessed by the FES-CV, the conflict subscale, generated different results in the univariate and multivariate analysis--family conflict was less important in the self-reports of homeless patients than in the self-reports of non-homeless patients, but this difference disappeared after adjustment for the sociodemographic factors. The remaining 9 subscales were consistent in the univariate and multivariate analyses, indicating that demographic factors did not strongly influence the results. As reported by the patients themselves, families in which patients with schizophrenia become homeless have a stronger a) intellectual-cultural orientation, b) achievement orientation, c) organization, and d) control; one possible interpretation for this is that patients with serious mental illnesses are less able to meet the high expectations of such families and, thus, are more likely to be extruded from the families or to leave on their own. Patients with schizophrenia who become homeless also report that their families have weaker a) cohesion, b) moral-religious emphasis, c) independence, and d) active-recreational orientation; one possible interpretation for this is that such families are generally less supportive of individual family members with problems. However, some of the constructs considered by the FES-CV subscales are not fully consistent with Chinese cultural norms (e.g., the importance of 'independence' and a 'moral-religious emphasis') so one must be cautious in interpreting these subscale results. Efforts are needed to identify more culture-sensitive measures of family functioning in China.

4.2 Limitations

There are several limitations that need to be considered when interpreting these results. This was a large inpatient sample from one location in China; we are unable to determine how representative this sample is of all homeless individuals with schizophrenia in China. The 7-day duration of homelessness used as the operational definition of homelessness in this study was chosen arbitrarily; it may be too short to identify the chronically homeless subgroup of patients who are most in need of social services. The assessment of family function was based on a self-completion instrument completed by individuals who had been hospitalized for two to three months at the time they completed the instrument and, in the case of the homeless group, may have been separated from their family for some time prior to hospitalization; this could introduce substantial recall bias. Moreover, all respondents had schizophrenia so their interpretation of family functioning may have been affected by their illness. Other factors that may affect homelessness among mentally ill individuals such as the personality and coping skills of the patients, and the number, age, and socio-economic status of the patients' close relatives were not considered. The very large sample resulted in many small but statistically significant differences between the groups; one needs to be cautious to avoid over-interpreting these small differences. Finally, the evaluation of family functioning was based on a scale for which some of the subscales have weak internal consistency: previous studies with the FES-CV [6] have shown that the Cronbach alpha values for the expressiveness, independence, achievement orientation, active-recreational orientation, moral-religious emphasis, and control subscales are all below 0.60, indicating that the items in these subscales are not assessing a distinct construct. Future research about this important topic will need to address these complex issues.

4.3 implications

This study identifies both demographic characteristics of patients and characteristics of patients' families that are independently associated with homelessness among individuals with schizophrenia. These results need to be confirmed by simultaneously obtaining information on family function from patients' family members and by using other measures of family functioning. The next step will be to see if these retrospectively identified risk factors for homelessness can prospectively predict which patients will become homeless. If they can, then clinicians must develop and test interventions aimed at reducing this very negative outcome (i.e., homelessness) for persons with serious mental disorders.

Conflict of interest

The authors declare that they have no conflict of interest.

Funding

The Fifth Ren Min Hospital of Xiangtan provided 50,000 Chinese Yuan to support this study.

Ethics review

The study was approved by the Ethics Committee of The Fifth Ren Min Hospital of Xiangtan.

informed consent

All participants provided written informed consent for participation in this study.

Acknowledgement

The Xiangtan Medical Association provided policy support and human resources for this project.

References

[1.] Chen JL, Guo XF, Chen JD. [Introduction to research about homeless patients with schizophrenia]. Guo Ji Jing Shen Bing Xue Za Zhi. 2014; 41(1): 56-58. Chinese

[2.] Schlosser DA, Pearson R, Perez VB, Loewy RL. Environmental risk and protective factors and their influence on the emergence of psychosis. Adolesc Psychiatry (Hilversum). 2012; 2(2): 163-171

[3.] Psychiatry Branch of the Chinese Medical Association. [China Classification and Diagnostic Criteria for Mental Disorders, 3rd Edition]. Shandong: Shandong Science and Technology Press; 2001. Chinese

[4.] Wang XD, Wang XL, Ma H. [Updated Version of Mental Health Rating Scale Manual ]. Beijing: Chinese Mental Health Magzine (suppl); 1999. pp: 263-267. Chinese

[5.] Hwang SW, Kirst MJ, Chiu S, Tolomiczenko G, Kiss A, Cowan L. Multidimensional social support and the health of homeless individuals. J Urban Health. 2009; 86(5): 791-803. Epub 2009 Jul 23. doi: http://dx.doi.org/10.1007/s11524-009-9388-x

[6.] Phillips MR. [Family Environment Scale--Chinese Version (FES-CV)]. In: Wang XD, Wang XL, Ma H, editors. [Handbook of Mental Health Rating Scales (updated version)]. Beijing: Chinese Mental Health magazine; 1999. p. 134-142. Chinese

[7.] Xu P, Yang JH. [Correlation between family environment and psychological health of teenager with schizophrenia disease]. Zhongguo Jian Kang Xin Li Xue Za Zhi. 2007; 15(2): 157-159. Chinese. doi: http://dx.doi.org/10.3969/j.issn.1005-1252.2007.02.025

[8.] Lv F, Gao H, Liang JG, Li P, Liu JT, Yu XJ. [A controlled study of family relations and parental rearing styles of patients with schizophrenia]. Zhong Hua Jing Shen Ke Za Zhi. 2001; 4: 42-44. Chinese. doi: http://dx.doi.org/10.3760/j:issn:1006-7884.2001.04.011

[9.] Amaresha AC, Venkatasubramanian G. Expressed emotion in schizophrenia: an overview. Indian J Psychol Med. 2012; 34: 12-20. doi: http://dx.doi.org/10.4103/0253-7176.96149

[10.] Masanet MJ, Lacruz M, Asencio A, Bellver F, Montero I. [Emotional family environment and clinical profile in schizophrenia]. Actas Luso Esp Neurol Psiquiatr Cienc Afines. 1997; 25(3): 159-66. Spanish

[11.] Jiang YH, He JY, Liang CS, Li RJ, Hou ZY, Zhang JX. [Effects of synthetical intervention on family environment in rural schizophrenia]. Zhong Hua Jing Shen Ke Za Zhi. 2004; 37(2): 99-102. Chinese. doi: http://dx.doi.org/10.3760/ j:issn:1006-7884.2004.02.011

[12.] Zhou GZ, Sun ZM. [Relationship between family environment and relapse schizophrenia patients]. Zhongguo Jian Kang Xin Li Xue Za Zhi. 2005; 13(4): 256-258. Chinese. doi: http://dx.doi.org/10.3969/j.issn.1005-1252.2005.04.006

(received, 2014-10-27; accepted, 2015-06-20)

Jinliang Chen obtained a Bachelor's degree in psychiatry from the Qiqiha'er Medical School in 2006. In 2013, he graduated from Zhong Nan University with a Master's degree in psychiatry and mental health. Since 2007, he has been working as an attending physician and deputy director of the Second Psychiatric Ward at the Fifth Ren Min Hospital of Xiangtan. His research interests are psychopharmacology and the psychiatric epidemiology of homelessness among persons with serious mental disorders.

Jinliang CHEN (1) *, Jindong CHEN (2), Shuchun LI (1), Jun LIU (1), Guohua OUYANG (1), Wenxuan LUO (1), Xiaofeng GUO (2), Ting LI (1), Kaijie LI (1), Zhenkuo LI (1), Gan WANG (1)

(1) Fifth Ren Min Hospital of Xiangtan, Hunan, Xiangtan, Hunan Province, China

(2) Mental Health Research Center, Xiang Ya Second Hospital of Zhong Nan University, Changsha, Hunan Province, China

* Correspondence: 125592215@qq.com

A full-text Chinese translation of this article will be available at htp://dx.doi.org/10.11919/j.issn.1002-0829.214162 on August 6, 2015.

Table 1. Comparison of basic characteristics of two groups

characteristics                   homeless group    non-homeless
                                     (n=1856)      group (n=1728)

male [n (%)]                       1216 (65.5%)     1088 (63.0%)
mean (sd) age                       39.1 (7.9)       36.5 (8.7)
rural residency [n (%)] (a)        1598 (86.6%)     1215 (70.3%)
from Xiangtan [n (%)]              704 (37.9%)      1536 (88.9%)
Educational level [n (%)]
  primary school or illiterate     1765 (95.1%)     912 (52.8%)
  middle school                     64 (3.4%)       413 (23.9%)
  high school or above              27 (1.5%)       403 (23.3%)
Marital status [n (%)]
  single                           1152 (62.1%)     1152 (66.7%)
  married or remarried             448 (24.1%)      320 (18.5%)
  divorced or widowed              256 (13.8%)      256 (14.8%)
Occupation [n (%)]
  stable job                       320 (17.2%)      256 (14.8%)
  temporary job                    960 (51.7%)      640 (37.0%)
  unemployed                       576 (31.0%)      832 (48.1%)
non-Han ethnicity [n (%)]          190 (10.2%)       59 (3.4%)
mean (sd) total BPRS score          27.9 (2.8)       28.0 (3.2)
  at time of evaluating
  family functioning

characteristics                         statistic             P

male [n (%)]                       [chi square] = 2.54      0.111
mean (sd) age                            t = 9.49          < 0.001
rural residency [n (%)] (a)       [chi square] = 140.68    < 0.001
from Xiangtan [n (%)]             [chi square] = 991.44    < 0.001
Educational level [n (%)]
  primary school or illiterate    [chi square] = 852.45    < 0.001
  middle school
  high school or above
Marital status [n (%)]
  single                          [chi square]  = 16.78    < 0.001
  married or remarried
  divorced or widowed
Occupation [n (%)]
  stable job                      [chi square]  = 113.23   < 0.001
  temporary job
  unemployed
non-Han ethnicity [n (%)]         [chi square]  = 64.43    < 0.001
mean (sd) total BPRS score               t = 1.00           0.317
  at time of evaluating
  family functioning

BPRS, Brief Psychiatric Rating Scale

(a) there were 10 homeless patients for whom the location of
residence was not determined so the denominator for this measure
in the homeless group was 1846.

Table 2. Comparison of subscale scores of the Chinese version of
the Family Environment Scale (FES-CV) between homeless and non-
homeless inpatients with schizophrenia

subscale                             homeless group    non-homeless
                                     (n=1856) mean    group (n=1728)
                                          (sd)          mean (sd)

Cohesion                              5.34 (2.50)      5.98 (2.47)
Expressiveness                        4.72 (1.59)      4.72 (1.98)
Conflict                              4.48 (1.48)      5.31 (1.62)
Independence                          5.00 (1.49)      5.91 (1.47)
Achievement orientation               5.45 (1.94)      5.16 (2.50)
Intellectual-cultural orientation     4.03 (2.31)      3.58 (2.31)
Active-recreational orientation       4.03 (1.83)      4.43 (2.37)
Moral-religious emphasis              4.48 (1.48)      5.33 (1.60)
Organization                          6.03 (1.96)      5.21 (2.19)
Control                               4.52 (1.73)      3.84 (2.29)

subscale                               t        P

Cohesion                             7.67    < 0.001
Expressiveness                       0.03     0.975
Conflict                             16.08   < 0.001
Independence                         18.37   < 0.001
Achievement orientation              3.91    < 0.001
Intellectual-cultural orientation    5.83    < 0.001
Active-recreational orientation      5.69    < 0.001
Moral-religious emphasis             16.52   < 0.001
Organization                         11.86   < 0.001
Control                              9.97    < 0.001

Table 3. Multivariate logistic regression of
socio-demographic factors related to
homelessness in 3574 patients with
schizophrenia (a)

Variable (b)                  odds ratio   95% confidence
                                 (OR)      interval of OR

                                           lower   upper

Age                              1.29      1.25    1.32
Female                           4.82      3.56    6.55
BPRS total score                 1.84      1.68    2.01
Lives in rural community         2.74      2.00    3.75
Lives outside of Xiangtan       69.12      48.99   97.53
Educational level
  primary school illiterate      1.00       ---     ---
  middle school                  0.14      0.10    0.21
  high school or above           0.02      0.01    0.03
Marital status
  never married                  1.00       --      --
  married or remarried           2.68      2.01    3.58
  divorced                      21.61      14.21   32.85
Occupation
  stable job                     1.00       --      --
  temporary job                  6.82      4.58    10.19
  unemployed                     1.13      0.79    1.63

BPRS, Brief Psychiatric Rating Scale

(a) 10 individuals whose residency was not determined were
excluded from the analysis

(b) one other variable considered but dropped out of the stepwise
analysis was ethnicity (p=0.125)

Table 4. Multivariate logistic regression of the
relationship of family environment factors
assessed by the subscales of the Chinese
version of the Family Environment Scale
(FES-CV) to homelessness in 3584 patients
with schizophrenia after controlling for
socio-demographic variables (a)

Variable                             odds    95% confidence
                                     ratio   interval of OR
                                     (OR)
                                             lower   upper

Coherence                            0.59    0.54    0.65
Expressiveness                       1.01    0.93    1.10
Conflict                             0.48    0.35    1.66
Independence                         0.44    0.38    0.50
Achievement orientation              1.31    1.18    1.46
Intellectual-cultural orientation    1.86    1.68    2.06
Active-recreational orientation      0.62    0.57    0.67
Moral-religious emphasis             0.72    0.65    0.81
Organization                         1.98    1.80    2.19
Control                              1.12    1.03    1.23

(a) Adjusted for age, gender, severity of psychiatric symptoms at time
of evaluation, education, marital status, and occupational status.
Two variables (urban versus rural residence, and living outside of
Xiangtan) could not be included in the model because of collinearity
with included variables
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Title Annotation:Original research article
Author:Chen, Jinliang; Chen, Jindong; Li, Shuchun; Liu, Jun; Ouyang, Guohua; Luo, Wenxuan; Guo, Xiaofeng; L
Publication:Shanghai Archives of Psychiatry
Article Type:Report
Date:Jun 1, 2015
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