Printer Friendly

Common anticoagulant may cause skin lesions.

Byline: ANI

Washington, Sept 29 (ANI): Heparin, a commonly used anticoagulant, may cause skin lesions, a new study has found.

Published in CMAJ (Canadian Medical Association Journal), the study looked at 320 patients undergoing heparin injections over 12 months at The Hospital of The Johann Wolfgang Goethe University in Frankfurt, Germany. kin lesions caused by heparin may indicate the presence of a life-threatening decrease in the number of platelets, a condition called "heparin-induced thrombocytopenia" or a, in most cases self-limiting, allergic skin reaction.

Twenty-four patients exhibited heparin-induced skin lesions, considerably above the expected rate of 2 percent.

"During the study, we were surprised by the high number of patients with heparin-induced skin lesions," state Dr. Ralf Ludwig, University of Lubeck, and coauthors.

After clinical examination, they suggested "a delayed-type hypersensitivity response was the most common cause for all the observed lesions," which was confirmed by subsequent allergologic and histologic testing.

Significantly more women had hypersensitivity reactions. Pregnancy, obesity and long duration of current heparin treatment were associated with a delayed-type hypersensitivity reactions.

The authors write that physicians must be aware that skin lesions are a possibility with subcutaneous heparin therapy, and they raise awareness, that the underlying cause of the lesion should be determined. (ANI)

Copyright 2009 Asian News International (ANI) - All Rights Reserved.

Provided by an company
COPYRIGHT 2009 Al Bawaba (Middle East) Ltd.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2009 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Publication:Asian News International
Date:Sep 29, 2009
Previous Article:Janet Jackson 'vows to wear black for a year to mourn MJ's death'.
Next Article:Malaysia's appeals panel upholds whip-for-beer-drinking model's punishment.

Related Articles
Tick protein tapped to attack blood clots.
DR GARETH: My fear of wasps and bees makes summertime hell.
Warfarin induced benign acral cutaneous lesions in two cardiac patients with decreased protein C and S activity/Protein C ve S aktiviteleri dusuk...

Terms of use | Privacy policy | Copyright © 2021 Farlex, Inc. | Feedback | For webmasters