I read the Editor's Note about the magazine's decision to use the AP Stylebook over the Chicago Manual of Style and got a good laugh. Oh, the debates that have raged over the comma-no comma issue. At the library where I work as the communications manager, our librarians always put it in, and I always take it out, explaining that we follow AP style. They, meanwhile, are hanging on to what they learned in high school English. You should have heard the discussion when the Associated Press decided not to capitalize internet or web any longer!
Those of us who love the intricacies of grammar and language are fascinated by all the nuances that we know others don't understand. I've brought entire conversations to a halt explaining archaic punctuation marks and why they are so cool.
And you're right, 99 percent of your readers won't even notice.