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Coming soon to pharmacies in your town--we hope.

Every runner knows the pain--tendonitis, sprains, strains, bruises, maybe even arthritis--we've all been there. The usual alternatives include RICE (rest, ice, compression, and elevation) and NSAIDs (non-steroidal anti-inflammatory drugs such as aspirin and ibuprofen) but they have their limitations and risks. Here's news that every runner can appreciate.

In a recent study, 222 adults who had suffered a minor, painful sports injury within the past 72 hours were recruited for a multicenter, randomized, placebo-controlled, parallel design trial to determine the efficacy of an NSAID patch--topical anti-inflammatory medication applied directly to the injury site. Either diclofenac epolamine or a placebo topical patch was applied directly to the skin overlying the injured site twice a day for two weeks. Results of the study showed statistically significant pain relief via the medicated patch and more important, no side effects were observed.

The disadvantages of oral NSAIDs are related to their systemic effects, particularly renal and gastrointestinal risks. The advantage of being able to enjoy anti-inflammatory pain relief with a lower risk of systemic side effects is obvious. Medication seeps through the skin, affecting only the site of injury, and reducing exposure to the entire circulatory system and all organs of the body. European communities have had access to the NSAID patch for several years. Given the widespread use of oral NSAIDs, and the fact that over 100,000 people a year are hospitalized due to side effects, let's hope for speedy approval from the Food and Drug Administration. This would be news we could use.

(Journal of Pain Symptom Management, 2000, Vol. 19, No. 4, pp. 287-294)
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Title Annotation:testing of non-steroidal anti-inflamatory drug patches
Publication:Running & FitNews
Article Type:Brief Article
Geographic Code:1USA
Date:Oct 1, 2000
Words:264
Previous Article:The Clinic.
Next Article:Exercise de-stresses.
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