Printer Friendly

Cold-fighting cells.

The immune system has two ways of dealing with foreign invaders--with a genearlized response, called cellular immunity, and a more specific response that involves antibodies. Susan C. Kiley and her colleagues at the Food and Drug Administration in Bethesda, Md., and George Washington University in Washington, D.C., are studying the action of cytotoxic T lymphocytes, cellular immune responders that attack foreign or infected cells. They have found a genetic factor in the ability of the cellular immune system to fight flu viruses.

They added T lymphocytes from 51 people to influenza-A infected cells. Cell types were defined by their HLA genes, a set of genes coding for proteins involved in cell recognition. There was a correlation between genetic subtype and disease-fighting ability -- cells bearing HLA-DR4 genes were better able to kill infected cells, and HLA-DR7 cells were less able, than the rest of the subtypes tested. "The cells of some people seem to be more reactive in response to infection by viruses than others," says Kiley. "We speculate that means they're more protective, but that would have to be followed up in future studies."
COPYRIGHT 1985 Science Service, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1985, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:T lymphocytes
Author:Silberner, Joanne
Publication:Science News
Date:Oct 12, 1985
Words:185
Previous Article:... and potential deaths from superfires.
Next Article:Herpes babies.
Topics:


Related Articles
Killer cells, MHC, factors in AIDS?
Battle of the T-cells.
T cells cure leukemic mice.
A kinder, gentler war against hepatitis B.
Vaccines for mucosal immunity to combat emerging infectious diseases.
Spontaneous remission of B-cell chronic lymphocytic leukemia associated with T lymphocytic hyperplasia in bone marrow. (Case Reports).
American forces press service (Oct. 3, 2005): Pace issues guidance to help military 'shape the future'.
Electronics recycling bill advances.
Cells' root: adult stem cells have a master gene.
Cell of Cells: The Global Race to Capture and Control the Stem Cell.

Terms of use | Copyright © 2016 Farlex, Inc. | Feedback | For webmasters