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Cognitive and walking symptoms are clues.

"This study is a useful addition to the literature. It takes accepted criteria for Lewy body disease with dementia (DLB and PDD) into account and uses a simple sale that should easily differentiate typical AD from PDD and DLB. None of the criteria will be a surprise to clinicians seeing patients with dementia. Given that treatments for AD and DLB are mostly supportive, this scale is unlikely to change clinical practice dramatically except for alerting physicians that a trial of movement-facilitating therapies such as levodopa/carbidopa and aggressive physical therapy is indicated, and that standard neuroleptics should be avoided. A more difficult clinical distinction (not addressed in this study) is the patient with cognitive symptoms and Parkinsonism who may have DLB, atypical AD, or frontotemporal lobar degeneration. In general, any patient with cognitive symptoms and walking trouble should be referred to a specialty center."

RICHARD O'BRIEN, MD, PhD, Neurologist, Duke

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Title Annotation:THE VIEW FROM DUKE
Author:O'Brien, Richard
Publication:Duke Medicine Health News
Article Type:Brief article
Date:Mar 1, 2016
Words:150
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