Printer Friendly

Coenzyme Q10 Improves Results of Coronary Bypass Surgery.

Thirty patients scheduled for elective coronary artery bypass graft surgery were randomly assigned to receive 150-180 mg per day of coenzyme Q10 (CoQ10) or no CoQ10 (control group) for 7 to 10 days preoperatively. Compared with the control group, the CoQ10 group had significantly fewer reperfusion arrhythmias, had a significantly lower total inotropic requirement, required significantly less mediastinal drainage, required significantly fewer blood transfusions (mean, 630 ml vs. 990 ml; p = 0.05) and other blood products, and had a shorter mean length of hospital stay (7.1 days vs. 10.3 days; 31% decrease; p = 0.02).

Comment: Cardiopulmonary bypass, which occurs during coronary artery bypass graft surgery, is known to induce oxidative stress and to decrease antioxidant levels. CoQ10 functions as an antioxidant and also as an important cofactor for energy production. The results of the present study indicate that supplementation with CoQ10 can improve clinical outcome in patients undergoing coronary artery bypass graft surgery. The reduction in the length of hospital stay and in the need for various medications and procedures would probably save at least $5,000 per patient.

Makhija N et al. The role of oral coenzyme Q10 in patients undergoing coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth. 2008;22:832-839.

by Alan R. Gaby, MD
COPYRIGHT 2009 The Townsend Letter Group
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 2009 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Publication:Townsend Letter
Article Type:Brief article
Geographic Code:1USA
Date:Jun 1, 2009
Previous Article:Red Yeast Rice Saves Lives.
Next Article:Coenzyme Q10 for Heart Failure: the Controversy.

Terms of use | Privacy policy | Copyright © 2021 Farlex, Inc. | Feedback | For webmasters |