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CoQ10 aids chronic heart failure patients.


Coenzyme Q10 supplementation improves cardiac function in patients with stable chronic heart failure, Italian researchers recently reported. *


Because plasma CoQ10 levels are depressed in patients with chronic heart failure, the scientists sought to determine whether oral CoQ10 supplementation could improve such patients' prognoses. The four-phase, double-blind, placebo-controlled, crossover trial enrolled 23 male and female patients with stable chronic heart failure. In the first phase, patients received 300 mg of CoQ10 per day. In the second phase, they received the same dose of CoQ10 and supervised exercise training. In a third phase, subjects received placebo, and in the fourth, they received placebo plus exercise.

Oral CoQ10 improved the heart's functional capacity, the ability of key blood vessels to dilate, and the contractility of the heart's left ventricle in patients with stable chronic heart failure. CoQ10's effects were even more pronounced when used in conjunction with exercise.


* Belardinelli R, Mucaj A, Lacalaprice F, et al. Coenzyme Q10 and exercise training in chronic heart failure. Eur Heart J. 2006 Nov;27(22):2675-81.
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Title Annotation:In The NEWS
Author:Kiefer, Dale
Publication:Life Extension
Article Type:Brief article
Date:Apr 1, 2007
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