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Chiral separations by capillary electrophoresis.


Chiral separations by capillary electrophoresis.

Ed. by Ann Van Ecekhaut and Yvette Michotte.

CRC Press


525 pages



Chromatographic science series; 100


Louis Pasteur discovered in 1848 that some molecules are right-handed and some left-handed, and by the end of the 19th century, studies were showing pharmaceutical differences between the two forms of otherwise identical molecules. It was not until the 1980s, however, that technology allowed mass chiral analysis and separation. One of the techniques that has proven effective in chiral separation is capillary eletrophoresis, and pharmaceutical chemists explain methods and applications. Their topics include the pharmacological importance of chiral separations, cyclodextrin-mediated chiral separations, macrocyclic antibiotics as chiral selectors, chiral ligand exchange capillary electrophoresis, chiral separations by micellar electrokinetic chromatography, quantitative analysis in pharmaceutical analysis, analyzing chiral drugs in body fluids, enantioseparations by capillary electrochromatography, and chiral separations with microchip technology.

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Publication:SciTech Book News
Article Type:Book review
Date:Jun 1, 2010
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