Printer Friendly

Chemical basis of a biological clock.

Chemical basis of a biological clock

The ticking of a fruit fly's biological clock involves a chemical called a proteoglycan, a long chain of sugar subunits attached to a protein. This result, reported by Michael Rosbash of Brandeis University in Waltham, Mass., comes from studies of a fly gene known as period (abbreviated as per), which is required for the insect's biological rhythms. By moving pieces of DNA into fly reproductive cells, Rosbach located the per gene on a segment of DNA that is active in the embryonic nervous system and again late in the pupal stage and in adulthood, especially in the fly head. The nucleotide sequence of the per gene was determined, and its predicted product resembles a mammalian proteoglycan. In further experiments, Rosbach showed "the per gene does indeed code for a proteoglycan.'
COPYRIGHT 1986 Science Service, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1986, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

Article Details
Printer friendly Cite/link Email Feedback
Author:Miller, Julie Ann
Publication:Science News
Date:May 24, 1986
Previous Article:...And to muscle.
Next Article:Down the road to skin ....

Related Articles
A light touch changes the biological clock.
Got no rhythm: stalling biological clocks.
Lighting up biological clocks; genes from glowing organisms illuminate circadian rhythms.
Found: mouse circadian rhythm gene.
Biological clocks fly into view.
Frozen in time: cells' clocks tick on.
Gene differs in early birds and night owls.
Shining light on a clock's proteins.
Fly naps inspire dreams of sleep genetics.
Protein may help the eyes tell time.

Terms of use | Copyright © 2016 Farlex, Inc. | Feedback | For webmasters