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Cell junctions; adhesion, development, and disease.


Cell junctions; adhesion, development, and disease.

Ed. by Susan E. LaFlamme and Andrew Kowalczyk.



301 pages




Of particular interest to cell and molecular biologists, cancer researchers, oncologists, biochemists, and researches in pharmaceuticals, these 14 comprehensive articles provide significant insights into cell-matrix junctions, cell-cell junctions and the cross-talk between cell-matrix and cell-cell adhesion. Papers cover elementary integrin signaling, integrin signaling through focal adhesion kinase, the Paxillin family and tissue remodeling, adhesion dynamics in motile cells, integrin trafficking, hemidesmosomes and their components (adhesion v. signaling), cell matrix adhesions in three dimensions, cell-cell junctions, signaling to and through the endothelial adherens junction, gap junctions (connexin functions), tight junctions in simple and stratified epithelium, desmosomes in development and disease, cadherin trafficking and junction dynamics, and cross-talk in cell-cell and cell-matrix adhesions. Each article includes references and the editors provide a full index.

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Publication:SciTech Book News
Article Type:Brief article
Date:Sep 1, 2008
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