Capsaicin eases Dyspepsia. (Clinical Capsules).
Thirty patients with functional dyspepsia were randomized to receive a daily capsule of either 2.5 g of red pepper powder or placebo for 5 weeks. The capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide) content was 0.7 mg/g of red pepper powder (N. Engl. J. Med. 346:947-48, 2002). After 3 weeks, the scores for overall symptoms, epigastric pain and fullness, nausea, and early satiety were all significantly reduced in the patients treated with capsaicin but not in those given placebo. Capsaicin is thought to desensitize gastric nociceptive C fibers, which carry pain sensations to the central nervous system.
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|Author:||Kubetin, Sally Koch|
|Publication:||Internal Medicine News|
|Date:||May 15, 2002|
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