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Capsaicin eases Dyspepsia. (Clinical Capsules).

Capsaicin was more effective than placebo for easing the symptoms of functional dyspepsia in a small trial, reported Dr. Mauro Bortolotti of the University of Bologna (Italy) and his associates.

Thirty patients with functional dyspepsia were randomized to receive a daily capsule of either 2.5 g of red pepper powder or placebo for 5 weeks. The capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide) content was 0.7 mg/g of red pepper powder (N. Engl. J. Med. 346[12]:947-48, 2002). After 3 weeks, the scores for overall symptoms, epigastric pain and fullness, nausea, and early satiety were all significantly reduced in the patients treated with capsaicin but not in those given placebo. Capsaicin is thought to desensitize gastric nociceptive C fibers, which carry pain sensations to the central nervous system.
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Author:Kubetin, Sally Koch
Publication:Internal Medicine News
Geographic Code:4EUIT
Date:May 15, 2002
Words:127
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