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CROP GENETICS INTERNATIONAL RECEIVES PATENT; EUROPEAN PATENT COVERS INCIDE(TM) CONCEPT

 CROP GENETICS INTERNATIONAL RECEIVES PATENT;
 EUROPEAN PATENT COVERS INCIDE(TM) CONCEPT
 HANOVER, Md., Oct. 14 /PRNewswire/ -- Crop Genetics International (NASDAQ: CROP) announced today that the European Patent Office granted a patent for the first of a series of patent applications for the company's InCide(TM) Plant Vaccine Technology.
 Patent No. 0125468 covers the broad concept of using modified endophytes, microorganisms which live in the vascular tissues of plants, to control plant pests. Using the unique technology disclosed in this patent and other pending patent applications, CGI is developing plant vaccine systems in which plant seeds are inoculated with InCide products to provide season-long and environmentally compatible pest control.
 "We're very pleased to receive this first InCide patent," said Dr. Peter Carlson, chief scientist of CGI and inventor of the InCide Technology. Carlson explained that this European patent covers endophytes modified using the tools of genetic hybridization and cell fusion; subsequent applications cover endophytes modified using recombinant DNA techniques. Carlson said the internally acting InCide plant vaccines dispense either a biological insecticide or fungicide from within the vascular system of the crop. Unlike conventional, externally applied pesticidal products, InCide biologicals are protected by the plant and not exposed to the degrading forces of rain, wind and sunlight. According to Carlson, CGI's InCide products are designed to provide effective pest control throughout the growing season, thereby eliminating the need for multiple chemical spray applications.
 Currently the company has two inCide products under development: a vaccine to protect corn from a major insect pest and a vaccine to protect rice from a major fungal disease. Using recombinant DNA technology, the company genetically modifies endophytes by inserting specific biotoxin encoding genes from other microorganisms. These genetically modified endophytes are incorporated into the crop plant through inoculation of the crop's seed. InCide plant vaccine products are designed to reproduce in the living plant's vascular system after the seed germinates. Throughout the crop's growth cycle, the vaccine consistently produces a biotoxin which protects the plant from devastating insect or fungal pests.
 Crop Genetics International Corporation is engaged in the discovery, development and commercialization of novel crop protection systems which substitute biopesticides for synthetic chemicals. The InStar(TM) Division, using recombinant DNA technology is developing plant vaccine systems to provide season-long and environmentally compatible pest control. The X-tend(TM) Division is developing herbicidal bacterial agents for control of a broad range of weed species. The Kleentek(TM) Division has developed and now markets disease-free, high yielding sugarcane seed products.
 -0- 10/14/92
 /CONTACT: Joseph Kelly of Crop Genetics International, 301-621-2900, or 410-712-7170/
 (CROP) CO: Crop Genetics International ST: Maryland IN: SU: PDT


CC-JS -- PH020 -- 0082 10/14/92 16:56 EDT
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Date:Oct 14, 1992
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