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CDC updates urine testing guidelines for Zika detection.

NEW DATA HAS LED the Centers for Disease Control and Prevention to issue updated guidance on urine testing for Zika infection.

In May, the public health agency reported that recent data suggest Zika virus RNA can persist in urine for at least two weeks after the initial onset of symptoms.

Given the new data, CDC issued interim guidance that Zika virus real-time reverse transcription-polymerase chain reaction testing should be performed on both urine and serum specimens collected within seven days of the onset of symptoms.

The test should also be performed on urine samples collected within 14 days of the onset of symptoms, with a positive result in either specimen confirming a Zika infection. However, CDC said a negative test result does not necessarily rule out Zika infection.

According to CDC, evidence from viruses similar to Zika suggest that Zika's incubation period is likely a few days to 14 days.

The interim guidance was published in the May 13 issue of CDC's Morbidity and Mortality Weekly Report and sent via CDC's Health Alert Network.

As of June 22 in U.S. states, CDC reported no locally acquired mosquito-borne cases of Zika and 819 travel-associated cases. In U.S. territories, CDC reported nearly 1,900 locally acquired and six travel-associated cases.

In the U.S., 287 pregnant women have tested positive for Zika virus as of June 23, and 250 pregnant women in U.S. territories have as well, according to CDC's pregnancy registries.

For a copy of the interim testing guidelines, visit http://emergency.cdc. gov. To stay abreast of CDC's Zika updates, visit

For an easy-to-share fact sheet on Zika, visit

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Author:Krisberg, Kim
Publication:The Nation's Health
Date:Aug 1, 2016
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