Printer Friendly

CD4 counts and AIDS survival.

Last fall, preliminary findings hinted that AIDS patients taking the drug zidovudine (AZT) have a better chance of prolonging their survival if their levels of certain immune cells, called CD4, stay above 50 cells per cubic millimeter of blood (SN: 11/4/89, p.298). A retrospective study of 55 people with AIDS or severe AIDS-related complex (ARC) has now confirmed that finding, reports a research group headed by Robert Yarchoan of the National Cancer Institute in Bethesda, Md. Patients "were very unlikely to die from HIV infection as long as their CD4 counts remained at 50 cells/[mm.sup.3] or higher," the team writes in the Aug. 1 ANNALS OF INTERNAL MEDICINE.

Of the 44 patients who died during the four-year study period, 40 had known CD4 levels below the critical limit within the six months prior to death, the researchers say. They emphasize that a CD4 count below 50 should not be viewed as a sign of imminent death; some patients in the study survived more than three years after their counts dropped below the critical level.
COPYRIGHT 1991 Science Service, Inc.
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1991, Gale Group. All rights reserved. Gale Group is a Thomson Corporation Company.

Article Details
Printer friendly Cite/link Email Feedback
Publication:Science News
Date:Aug 17, 1991
Words:180
Previous Article:Recognizing heart attacks in time.
Next Article:Surface diffusion with a hop, skip or dip.
Topics:


Related Articles
Receptor decoy shows promise against AIDS.
Antibody treatment joins AIDS battle.
Mysterious hormone forecasts AIDS onset.
No survival bonus from early AZT.
FDA conditionally OKs third AIDS drug.
AZT: attacking AIDS early and hard.
AIDS update '96: new drugs, new tests, new optimism mark recent AIDS research.
Rooting out dormant HIV-infected cells.
Questions about HIV Causing AIDS? Viral Load and T-Cell (CD4) Counts: Why They Really Matter.
AIDS treatment news denialist series.

Terms of use | Copyright © 2017 Farlex, Inc. | Feedback | For webmasters