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CALGENE RECEIVES 'BRASSICA' TRANSFORMATION PATENT; KEY TECHNOLOGY FOR PRODUCING GENETICALLY MODIFIED PLANT OILS

 DAVIS, Calif., Feb. 26 /PRNewswire/ -- Calgene Inc. (NASDAQ-NMS: CGNE) today announced that it has been granted U.S. patent no. 5,188,958 to genetically engineered Brassica cells from the U.S. Patent and Trademark Office. A patent with similar claims is in advanced stage of grant in Europe. Brassica is the genus name for a family of plants which includes among others, rapeseed, broccoli, cauliflower, cabbage and brussels sprout.
 The patents cover Brassica cells and their progeny which contain an Agrobacterium border region and a selectable marker. "This is the most efficient transformation method for Brassica species in the industry and is a key technology of Calgene's proprietary vegetable oils now in field trials," explained Vic Knauf, Calgene's vice president, Research.
 Rapeseed, from which canola oil is harvested, is the core crop in Calgene's genetically modified oils program. Calgene previously announced positive results in its efforts to produce a high stearate canola oil product with food applications and the development of proprietary rapeseed varieties that produce oil containing laurate, an important ingredient in detergents which is not normally present in canola. Calgene plans the first commercial production of its genetically engineered oils in 1995.
 "These patents represent valuable tools for Brassica transformation and we plan to license it to companies for applications other than rapeseed oil modification," said Roger Salquist, Calgene's chief executive officer. "This patent compliments our expanding portfolio of gene patents." The company has the first filed patents in Europe on plant desaturase, synthase, reductase and medium-chain thioesterase oil biosysnthesis genes and has corresponding U.S. patent applications pending.
 Calgene is an agribusiness biotechnology company that is developing improved plant varieties and plant products for the fresh tomato, cotton seed and special industrial and edible oils business.
 -0- 2/26/93
 /CONTACT: Andrew Baum or Carolyn Hayworth of Calgene, 916-753-6313/
 (CGNE)


CO: Calgene Inc. ST: California IN: MTC SU:

TM-TB -- SF004 -- 0819 02/26/93 11:38 EST
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Date:Feb 26, 1993
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