Printer Friendly

Breast implants linked to autoimmune disorder.

Breast Implants Linked to Autoimmune Disorder

NEW YORK CITY: In some patients, breast enlargement with silicone implants may precipitate scleroderma, a serious auto-immune disorder whose most prominent feature is severe skin-thickening that can restrict hand movement and facial expression, reports Harry Spiera, M.D., from the Division of Rheumatology at Mount Sinai School of Medicine in New York.

Scleroderma, a disease of unknown cause that occurs mostly in women and may include destructive changes in internal organs as well as skin, was diagnosed in five patients (two of whom had implants following a mastectomy) two to 21 years after they had breast enlargement surgery using silicone implants. Four patients had features of typical scleroderma and one patient had the clinical features of eosinophilic fasciitis, a rare but similar connective tissue disorder.

These five patients, said Dr. Spiera, represent nearly 5% of 113 new female patients with scleroderma who were seen during a period of seven years. "In contrast," he said, "only one (0.3%) of 286 new patients with rheumatoid arthritis [another auto-immune disease] who were seen during the same interval had had a breast implant. The difference was statistically significant and suggests a relationship between silicone [breast implants] and scleroderman." (The
COPYRIGHT 1989 Vegetus Publications
No portion of this article can be reproduced without the express written permission from the copyright holder.
Copyright 1989 Gale, Cengage Learning. All rights reserved.

Article Details
Printer friendly Cite/link Email Feedback
Title Annotation:scleroderma
Publication:Nutrition Health Review
Date:Jun 22, 1989
Previous Article:Use of acetaminophen linked to kidney disease.
Next Article:Botulism linked to cocaine use.

Related Articles
Breast implants and autoimmune disease.
Implants linked to disorders in children.
Opt-out deadline approaches for breast implant pact.
Implants almost exonerated.
FDA, new study dismiss link between breast implants and connective-tissue diseases.
Plaintiffs score victories in breast implant cases.
Plaintiff lawyers weigh impact of breast implant study.
Breast implants for reconstruction: a closer look.
Safety of breast implants still unclear.

Terms of use | Copyright © 2016 Farlex, Inc. | Feedback | For webmasters