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Blue light spots tiny endometriosis lesions. (Investigational Device).

NEW ORLEANS -- Endometriosis lesions preferentially absorb light of the blue spectrum, allowing detection of previously nonidentifiable microscopic lesions, Dr. Larry A. Demco reported.

The findings, from an ongoing study of more than 60 women with endometriosis, could have implications for earlier and more thorough treatment of the condition, he reported at an international congress sponsored by the Society of Laparoendoscopic Surgeons.

The laparoscopic spectral analysis of endometriosis involves the use of a specially adapted xenon light source, which is still under investigation and not yet available in the United States. The light source was used to deliver the blue light concurrently with the white light normally used to detect endometriosis.

A laparoscope was coupled to the light source. Next, lesions detected by both the white and blue light were compared, and biopsies of the lesions and satellite lesions were taken to confirm pathology, explained Dr. Demco of the University of Calgary (Alta.).

The black, red, and clear lesions typically detected using white light were visualized with both the white and blue spectrums, but microscopic lesions surrounding the classic macroscopic lesions were visualized only with the blue spectrum. Biopsies confirmed that endometriosis was present in these microscopic lesions as well, said Dr. Demco, who said he had no financial interest in the device.

Further, pain mapping has revealed that pain associated with endometriosis extends up to 27 mm from lesions visible with white light to areas that previously looked like normal peritoneum.

"There was something there; we just couldn't see it," Dr. Demco said, noting that pain mapping was also used in the spectral analysis study to confirm the clinical significance of the microscopic lesions.

The microscopic lesions were clearly associated with pain, and identification and treatment of the lesions will be improved using the blue light spectrum, he told this newspaper.
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Author:Worcester, Sharon
Publication:OB GYN News
Date:Dec 1, 2002
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