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Bioorganic and medicinal chemistry of fluorine.


Bioorganic and medicinal chemistry of fluorine.

Begue, Jean-Pierre and Daniele Bonnet-Delpon.

John Wiley & Sons


365 pages




Recent discoveries have led to increased interest and usage of fluorine in chemistry, and this well-illustrated text serves as a strong reference on the influence of fluorine on the structural properties of a molecule and on a molecule's biological behavior. With many examples of fluorinated drugs to illustrate fluorine's place in pharmaceutical science and development, Begue and Bonnet-Delpon, emeritus and current directors of research at the Centre National de la Recherche Scientifique, France introduce the structural, physical and chemical properties of fluoridated compounds and their preparations, and examine fluorinated analogues of natural products, fluorinated amino acids and peptides, and saccharidic derivatives. They also give a good overview of existing fluorinated pharmaceuticals and some in development, and include comprehensive references for further study. This is essential reading for pharmaceutical and medicinal chemists, researchers in organic chemistry and biochemistry, and advanced students.

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Publication:SciTech Book News
Article Type:Book review
Date:Sep 1, 2008
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